DPH6 diphthamine biosynthesis 6 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: DPH6provided by VGNC
Official Full Name: diphthamine biosynthesis 6provided by VGNC
Primary source: VGNC:VGNC:58300
See related: Ensembl:ENSCAFG00845024177
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: ATPBD4
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 30

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	30	NC_051834.1 (3066202..3261206, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	30	NC_006612.4 (3000875..3196175, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	30	NC_049251.1 (3228666..3423950, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	30	NC_049290.1 (2999857..3195107, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	30	NC_049771.1 (3099636..3295078, complement)

Chromosome 30 - NC_051834.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

REN187M05 (e-PCR)
- UniSTS:264434

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables diphthine-ammonia ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein histidyl modification to diphthamide	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: diphthine--ammonia ligase

Names: ATP binding domain 4

XP_038297825.1

EC 6.3.1.14

XP_038297826.1

EC 6.3.1.14

XP_038297828.1

EC 6.3.1.14

XP_038297829.1

EC 6.3.1.14

XP_038297830.1

EC 6.3.1.14

XP_038317555.1

EC 6.3.1.14

XP_038317556.1

EC 6.3.1.14

XP_038317557.1

EC 6.3.1.14

XP_038317558.1

EC 6.3.1.14

XP_038317559.1

EC 6.3.1.14

XP_038372307.1

EC 6.3.1.14

XP_038372308.1

EC 6.3.1.14

XP_038372309.1

EC 6.3.1.14

XP_038372310.1

EC 6.3.1.14

XP_038372311.1

EC 6.3.1.14

XP_038435902.1

EC 6.3.1.14

XP_038435903.1

EC 6.3.1.14

XP_038435904.1

EC 6.3.1.14

XP_038435905.1

EC 6.3.1.14

XP_038435906.1

EC 6.3.1.14

XP_038500164.1

EC 6.3.1.14

XP_038500165.1

EC 6.3.1.14

XP_038500167.1

EC 6.3.1.14

XP_038500168.1

EC 6.3.1.14

XP_038500169.1

EC 6.3.1.14

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051834.1 Reference ROS_Cfam_1.0

Range

3066202..3261206 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038441897.1 → XP_038297825.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038441900.1 → XP_038297828.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038441901.1 → XP_038297829.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038441898.1 → XP_038297826.1 diphthine--ammonia ligase isoform X2

UniProtKB/TrEMBL

A0A8C0K028, A0A8C0PTQ2, A0A8I3PHH9, A0A8I3PL89, A0A8P0SDP1

Related

ENSCAFP00845033627.1, ENSCAFT00845042902.1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038441902.1 → XP_038297830.1 diphthine--ammonia ligase isoform X4

UniProtKB/TrEMBL

A0A8C0PH74, A0A8I3PM71

Related

ENSCAFP00845033699.1, ENSCAFT00845042985.1

Conserved Domains (1) summary

cl00292
Location:2 → 104

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

XR_005304611.1 RNA Sequence
XR_005304612.1 RNA Sequence
XR_005304613.1 RNA Sequence
XR_005304614.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

NC_049290.1 Alternate UMICH_Zoey_3.1

Range

2999857..3195107 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038516379.1 → XP_038372307.1 diphthine--ammonia ligase isoform X1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038516381.1 → XP_038372309.1 diphthine--ammonia ligase isoform X3

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038516382.1 → XP_038372310.1 diphthine--ammonia ligase isoform X3

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038516380.1 → XP_038372308.1 diphthine--ammonia ligase isoform X2

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038516383.1 → XP_038372311.1 diphthine--ammonia ligase isoform X4

Conserved Domains (1) summary

cl00292
Location:2 → 104

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

XR_005347686.1 RNA Sequence
XR_005347687.1 RNA Sequence
XR_005347688.1 RNA Sequence
XR_005347689.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049771.1 Alternate UNSW_CanFamBas_1.0

Range

3099636..3295078 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038644236.1 → XP_038500164.1 diphthine--ammonia ligase isoform X1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038644239.1 → XP_038500167.1 diphthine--ammonia ligase isoform X3

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038644240.1 → XP_038500168.1 diphthine--ammonia ligase isoform X3

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038644237.1 → XP_038500165.1 diphthine--ammonia ligase isoform X2

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038644241.1 → XP_038500169.1 diphthine--ammonia ligase isoform X4

Conserved Domains (1) summary

cl00292
Location:2 → 104

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

XR_005415245.1 RNA Sequence
XR_005415246.1 RNA Sequence
XR_005415247.1 RNA Sequence
XR_005415248.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049251.1 Alternate UU_Cfam_GSD_1.0

Range

3228666..3423950 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038579974.1 → XP_038435902.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038579976.1 → XP_038435904.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038579977.1 → XP_038435905.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038579975.1 → XP_038435903.1 diphthine--ammonia ligase isoform X2

UniProtKB/TrEMBL

A0A8C0K028, A0A8C0PTQ2, A0A8I3PHH9, A0A8I3PL89, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038579978.1 → XP_038435906.1 diphthine--ammonia ligase isoform X4

UniProtKB/TrEMBL

A0A8C0PH74, A0A8I3PM71

Conserved Domains (1) summary

cl00292
Location:2 → 104

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

XR_005381426.1 RNA Sequence
XR_005381427.1 RNA Sequence
XR_005381428.1 RNA Sequence
XR_005381429.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

3000875..3196175 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038461627.1 → XP_038317555.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038461629.1 → XP_038317557.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038461630.1 → XP_038317558.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038461628.1 → XP_038317556.1 diphthine--ammonia ligase isoform X2

UniProtKB/TrEMBL

A0A8C0K028, A0A8C0PTQ2, A0A8I3PHH9, A0A8I3PL89, A0A8P0SDP1

Conserved Domains (1) summary

cd01994
Location:2 → 215

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_038461631.1 → XP_038317559.1 diphthine--ammonia ligase isoform X4

UniProtKB/TrEMBL

A0A8C0PH74, A0A8I3PM71

Conserved Domains (1) summary

cl00292
Location:2 → 104

AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.