ypel3 yippee-like 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ypel3provided by ZNC
Official Full Name: yippee-like 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-030516-4
See related: Ensembl:ENSDARG00000055510 AllianceGenome:ZFIN:ZDB-GENE-030516-4
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Ypel1; cb475; wu:fi27c07
Summary: Predicted to enable metal ion binding activity. Acts upstream of or within brain development; filopodium assembly; and glial cell differentiation. Predicted to be located in nucleolus. Is expressed in several structures, including central nervous system; pronephric duct; tail bud; ventral mesoderm; and yolk syncytial layer. Orthologous to several human genes including YPEL3 (yippee like 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (26186153..26191637, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (26055282..26060766, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development.
Title: yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development.

Submit: New GeneRIF Correction

General gene information

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Markers

AW153930 (e-PCR)
- UniSTS:205938

fe25a08.x1 (e-PCR)
- UniSTS:196325

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Schwann cell development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within brain development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within filopodium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within spinal cord oligodendrocyte cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein yippee-like 3

Names: proteim yippee-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212790.1 → NP_997955.1 protein yippee-like 3

See identical proteins and their annotated locations for NP_997955.1

Status: PROVISIONAL

Source sequence(s)

BC067578

UniProtKB/Swiss-Prot

Q6NWI4

Related

ENSDARP00000099958.3, ENSDART00000113843.5

Conserved Domains (1) summary

cl13152
Location:21 → 110

RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains