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    AR androgen receptor [ Pan troglodytes (chimpanzee) ]

    Gene ID: 747460, updated on 3-Apr-2024

    Summary

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    Official Symbol
    ARprovided by VGNC
    Official Full Name
    androgen receptorprovided by VGNC
    Primary source
    VGNC:VGNC:111790
    Locus tag
    CK820_G0033181
    See related
    Ensembl:ENSPTRG00000032525
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) X NC_072421.2 (65253214..65437940)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (65249306..65434032)

    Chromosome X - NC_072421.2Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene polyadenylate-binding protein 2-like Neighboring gene polycomb complex protein BMI-1-like Neighboring gene protein argonaute-3-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recognition and accommodation at the androgen receptor coactivator binding interface. Hur E, et al. PLoS Biol, 2004 Sep. PMID 15328534, Free PMC Article
    2. Evolution of the primate androgen receptor: a structural basis for disease. Choong CS, et al. J Mol Evol, 1998 Sep. PMID 9732460

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables estrogen response element binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in androgen receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in male gonad development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    androgen receptor
    Names
    androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
    dihydrotestosterone receptor
    nuclear receptor subfamily 3 group C member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009012.1 → NP_001009012.1  androgen receptor

      See identical proteins and their annotated locations for NP_001009012.1

      Status: PROVISIONAL

      Source sequence(s)
      U94177
      UniProtKB/Swiss-Prot
      O97775
      UniProtKB/TrEMBL
      A0A2J8L3J7
      Related
      ENSPTRP00000076864.1, ENSPTRT00000086173.1
      Conserved Domains (3) summary
      cd07073
      Location:664 → 909
      NR_LBD_AR; Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator
      cd07173
      Location:546 → 627
      NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
      pfam02166
      Location:6 → 446
      Androgen_recep; Androgen receptor

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072421.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      65253214..65437940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054676212.2 → XP_054532187.1  androgen receptor isoform X1

      UniProtKB/TrEMBL
      A0A2I3T1P9, A0A2J8L3K1, A0A6D2X4P4

    2. XM_024352970.2 → XP_024208738.2  androgen receptor isoform X2

    RNA

    1. XR_008541895.1 RNA Sequence

    2. XR_008541896.1 RNA Sequence

    3. XR_002941296.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O97775.1 GenPept UniProtKB/Swiss-Prot:O97775

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