phb2b prohibitin 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: phb2bprovided by ZNC
Official Full Name: prohibitin 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-430
See related: Ensembl:ENSDARG00000017728 AllianceGenome:ZFIN:ZDB-GENE-040718-430
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:86841
Summary: Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial inner membrane and plasma membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and solid lens vesicle. Orthologous to human PHB2 (prohibitin 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (29707123..29714339)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (29716562..29723778)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in mitochondrion organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: prohibitin-2b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002681.2 → NP_001002681.2 prohibitin-2b

Status: VALIDATED

Source sequence(s)

EB786418, EH508828, EH518571, EH533427

UniProtKB/TrEMBL

A0A8M1N0W4, F1R9C6

Related

ENSDARP00000022440.6, ENSDART00000023549.7

Conserved Domains (2) summary

smart00244
Location:49 → 209

PHB; prohibitin homologues

cd03401
Location:49 → 243

SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily