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    tads-1 Replication termination factor 2 [ Caenorhabditis elegans ]

    Gene ID: 173206, updated on 5-May-2024

    Summary

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    Gene symbol
    tads-1
    Gene description
    Replication termination factor 2
    Primary source
    WormBase:WBGene00007217
    Locus tag
    CELE_C01A2.5
    See related
    AllianceGenome:WB:WBGene00007217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitotic DNA replication termination. Predicted to be active in nucleus. Orthologous to human RTF2 (replication termination factor 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See tads-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (13384752..13387084)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene WWE domain-containing protein Neighboring gene Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein Neighboring gene Charged multivesicular body protein 2b

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Domain selection combined with improved cloning strategy for high throughput expression of higher eukaryotic proteins. Chen Y, et al. BMC Biotechnol, 2007 Jul 30. PMID 17663785, Free PMC Article
    2. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in DNA replication termination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic DNA replication termination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Replication termination factor 2
    NP_493355.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      13384752..13387084
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060954.8 → NP_493355.1  Replication termination factor 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493355.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O02209
      Conserved Domains (1) summary
      pfam04641
      Location:1 → 285
      Rtf2; Rtf2 RING-finger
    Nucleotide Protein
    Heading Accession and Version

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