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    F55F10.1 Midasin;VWFA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186322, updated on 23-Nov-2023

    Summary

    Gene symbol
    F55F10.1
    Gene description
    Midasin;VWFA domain-containing protein
    Primary source
    WormBase:WBGene00018898
    Locus tag
    CELE_F55F10.1
    See related
    AllianceGenome:WB:WBGene00018898
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in rRNA processing and ribosomal large subunit assembly. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of preribosome, large subunit precursor. Orthologous to human MDN1 (midasin AAA ATPase 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See F55F10.1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    20
    Sequence:
    Chromosome: IV; NC_003282.8 (4360837..4386531)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene serine--tRNA ligase Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Transaldolase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein eL8

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Midasin;VWFA domain-containing protein
    NP_001367899.1
    • Confirmed by transcript evidence
    NP_001368166.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4360837..4386531
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380187.2NP_001367899.1  VWFA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61851
      Conserved Domains (2) summary
      COG5271
      Location:6102124
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      cd01460
      Location:18722129
      vWA_midasin; VWA_Midasin: Midasin is a member of the AAA ATPase family. The proteins of this family are unified by their common archetectural organization that is based upon a conserved ATPase domain. The AAA domain of midasin contains six tandem AAA protomers. The ...
    2. NM_001380186.1NP_001368166.1  Midasin [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8E6W9
      Conserved Domains (1) summary
      COG5271
      Location:704355
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]