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    Wdr27 WD repeat domain 27 [ Mus musculus (house mouse) ]

    Gene ID: 71682, updated on 5-Mar-2024

    Summary

    Official Symbol
    Wdr27provided by MGI
    Official Full Name
    WD repeat domain 27provided by MGI
    Primary source
    MGI:MGI:1918932
    See related
    Ensembl:ENSMUSG00000046991 AllianceGenome:MGI:1918932
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610012K18Rik
    Summary
    Predicted to be located in nucleoplasm. Orthologous to human WDR27 (WD repeat domain 27). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 4.5), ovary adult (RPKM 0.4) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Wdr27 in Genome Data Viewer
    Location:
    17 A2; 17 8.95 cM
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (15005092..15163540, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (14784829..14943259, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene thrombospondin 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_41895 Neighboring gene predicted gene, 23352 Neighboring gene STARR-seq mESC enhancer starr_41897 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:15046536-15046719 Neighboring gene RIKEN cDNA 1600012H06 gene Neighboring gene STARR-positive B cell enhancer ABC_E9166 Neighboring gene PHD finger protein 10 Neighboring gene dynein light chain Tctex-type 2A3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    WD repeat-containing protein 27

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175173.3NP_780382.2  WD repeat-containing protein 27

      See identical proteins and their annotated locations for NP_780382.2

      Status: VALIDATED

      Source sequence(s)
      AK077050, AV277048
      Consensus CDS
      CCDS37443.1
      UniProtKB/Swiss-Prot
      Q8C5V5, Q8CA00
      Related
      ENSMUSP00000153717.2, ENSMUST00000228330.2
      Conserved Domains (3) summary
      COG2319
      Location:53236
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      15005092..15163540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524929.5XP_006524992.1  WD repeat-containing protein 27 isoform X4

      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514811
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_011246612.4XP_011244914.1  WD repeat-containing protein 27 isoform X3

      See identical proteins and their annotated locations for XP_011244914.1

      UniProtKB/TrEMBL
      A0A338P6H6
      Related
      ENSMUSP00000155992.2, ENSMUST00000232147.2
      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514822
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. XM_006524928.3XP_006524991.1  WD repeat-containing protein 27 isoform X3

      See identical proteins and their annotated locations for XP_006524991.1

      UniProtKB/TrEMBL
      A0A338P6H6
      Related
      ENSMUSP00000158649.2, ENSMUST00000238668.2
      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514822
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. XM_017317639.1XP_017173128.1  WD repeat-containing protein 27 isoform X1

      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514813
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    5. XM_017317640.3XP_017173129.1  WD repeat-containing protein 27 isoform X5

      Conserved Domains (2) summary
      sd00039
      Location:450487
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:450749
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    6. XM_006524925.5XP_006524988.1  WD repeat-containing protein 27 isoform X1

      See identical proteins and their annotated locations for XP_006524988.1

      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514813
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7. XM_006524926.5XP_006524989.1  WD repeat-containing protein 27 isoform X1

      See identical proteins and their annotated locations for XP_006524989.1

      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514813
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    8. XM_006524934.4XP_006524997.1  WD repeat-containing protein 27 isoform X8

      Conserved Domains (2) summary
      sd00039
      Location:278315
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:278577
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    9. XM_011246611.3XP_011244913.1  WD repeat-containing protein 27 isoform X2

      Conserved Domains (2) summary
      sd00039
      Location:514551
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:514811
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    10. XM_011246616.3XP_011244918.1  WD repeat-containing protein 27 isoform X7

      See identical proteins and their annotated locations for XP_011244918.1

      Conserved Domains (2) summary
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    11. XM_006524931.4XP_006524994.1  WD repeat-containing protein 27 isoform X6

      Conserved Domains (2) summary
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    12. XM_011246617.4XP_011244919.1  WD repeat-containing protein 27 isoform X7

      See identical proteins and their annotated locations for XP_011244919.1

      Conserved Domains (2) summary
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    13. XM_017317641.3XP_017173130.1  WD repeat-containing protein 27 isoform X9

      Conserved Domains (2) summary
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    14. XM_017317642.3XP_017173131.1  WD repeat-containing protein 27 isoform X10

      Conserved Domains (2) summary
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    15. XM_006524936.3XP_006524999.1  WD repeat-containing protein 27 isoform X11

      Conserved Domains (2) summary
      sd00039
      Location:73118
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:47235
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. XR_001782112.3 RNA Sequence

    2. XR_003952182.2 RNA Sequence

    3. XR_004939577.1 RNA Sequence