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    Btbd19 BTB domain containing 19 [ Mus musculus (house mouse) ]

    Gene ID: 78611, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Btbd19provided by MGI
    Official Full Name
    BTB domain containing 19provided by MGI
    Primary source
    MGI:MGI:1925861
    See related
    Ensembl:ENSMUSG00000073771 AllianceGenome:MGI:1925861
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9530048O09Rik
    Summary
    Orthologous to human BTBD19 (BTB domain containing 19). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 3.0), spleen adult (RPKM 2.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Btbd19 in Genome Data Viewer
    Location:
    4 D1; 4 53.41 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116976409..116983531, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (117119219..117125658, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B, subunit 3 Neighboring gene predicted gene, 22335 Neighboring gene STARR-seq mESC enhancer starr_11152 Neighboring gene Ptch2 Hedgehog-responsive enhancers Neighboring gene patched 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116793139-116793326 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116797070-116797223 Neighboring gene STARR-positive B cell enhancer ABC_E2707 Neighboring gene dynein light chain Tctex-type 4 Neighboring gene STARR-positive B cell enhancer ABC_E7981 Neighboring gene polo like kinase 3 Neighboring gene bestrophin 4, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein 19
    Names
    BTB (POZ) domain containing 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001384196.1 → NP_001371125.1  BTB/POZ domain-containing protein 19

      Status: VALIDATED

      Source sequence(s)
      AL671866
      UniProtKB/TrEMBL
      S4R1I0
      Related
      ENSMUSP00000138230.2, ENSMUST00000183310.2
      Conserved Domains (2) summary
      cd18294
      Location:15 → 108
      BTB_POZ_BTBD19; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 19 (BTBD19)
      cd18494
      Location:125 → 197
      BACK_BTBD19; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 19 (BTBD19)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      116976409..116983531 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164557.1 → XP_036020450.1  BTB/POZ domain-containing protein 19 isoform X6

      Conserved Domains (1) summary
      cd18294
      Location:15 → 108
      BTB_POZ_BTBD19; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 19 (BTBD19)

    2. XM_036164556.1 → XP_036020449.1  BTB/POZ domain-containing protein 19 isoform X5

      Conserved Domains (2) summary
      cd18294
      Location:15 → 108
      BTB_POZ_BTBD19; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 19 (BTBD19)
      cl28903
      Location:125 → 157
      BACK; BACK (BTB and C-terminal Kelch) domain

    3. XM_036164552.1 → XP_036020445.1  BTB/POZ domain-containing protein 19 isoform X1

      Conserved Domains (2) summary
      cd18294
      Location:15 → 108
      BTB_POZ_BTBD19; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 19 (BTBD19)
      cd18494
      Location:125 → 197
      BACK_BTBD19; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 19 (BTBD19)

    4. XM_036164553.1 → XP_036020446.1  BTB/POZ domain-containing protein 19 isoform X2

      Conserved Domains (1) summary
      cd18494
      Location:82 → 154
      BACK_BTBD19; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 19 (BTBD19)

    5. XM_036164554.1 → XP_036020447.1  BTB/POZ domain-containing protein 19 isoform X3

      Conserved Domains (1) summary
      cd18494
      Location:61 → 133
      BACK_BTBD19; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 19 (BTBD19)

    6. XM_036164558.1 → XP_036020451.1  BTB/POZ domain-containing protein 19 isoform X7

      Conserved Domains (1) summary
      cl28903
      Location:82 → 114
      BACK; BACK (BTB and C-terminal Kelch) domain

    7. XM_036164555.1 → XP_036020448.1  BTB/POZ domain-containing protein 19 isoform X4

      Conserved Domains (1) summary
      cd18494
      Location:82 → 154
      BACK_BTBD19; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 19 (BTBD19)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001033187.1: Suppressed sequence

      Description
      NM_001033187.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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