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    Lysmd2 LysM, putative peptidoglycan-binding, domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 70082, updated on 8-May-2024

    Summary

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    Official Symbol
    Lysmd2provided by MGI
    Official Full Name
    LysM, putative peptidoglycan-binding, domain containing 2provided by MGI
    Primary source
    MGI:MGI:1917332
    See related
    Ensembl:ENSMUSG00000032184 AllianceGenome:MGI:1917332
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2210402C18Rik
    Summary
    Is expressed in bladder and glans of male genital tubercle. Orthologous to human LYSMD2 (LysM domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in ovary adult (RPKM 15.0), lung adult (RPKM 15.0) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lysmd2 in Genome Data Viewer
    Location:
    9 D; 9 42.32 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (75532403..75545055)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (75625121..75637773)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene tropomodulin 3 Neighboring gene STARR-positive B cell enhancer mm9_chr9:75407347-75407647 Neighboring gene STARR-positive B cell enhancer mm9_chr9:75429888-75430189 Neighboring gene tropomodulin 2 Neighboring gene STARR-positive B cell enhancer mm9_chr9:75478519-75478819 Neighboring gene secretogranin III Neighboring gene STARR-seq mESC enhancer starr_24672 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models. Soulez M, et al. Mol Cell Biol, 2019 Mar 15. PMID 30642949, Free PMC Article
    2. Diversification of stem cell molecular repertoire by alternative splicing. Pritsker M, et al. Proc Natl Acad Sci U S A, 2005 Oct 4. PMID 16183747, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    lysM and putative peptidoglycan-binding domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027309.2 → NP_081585.2  lysM and putative peptidoglycan-binding domain-containing protein 2

      See identical proteins and their annotated locations for NP_081585.2

      Status: VALIDATED

      Source sequence(s)
      AC123832, DT905233
      Consensus CDS
      CCDS40693.1
      UniProtKB/Swiss-Prot
      Q80ZR2, Q9D7V2
      UniProtKB/TrEMBL
      G3X915
      Related
      ENSMUSP00000034702.5, ENSMUST00000034702.6
      Conserved Domains (2) summary
      cd00118
      Location:71 → 115
      LysM; Lysine Motif is a small domain involved in binding peptidoglycan
      COG1388
      Location:53 → 122
      LysM; LysM repeat [Cell wall/membrane/envelope biogenesis]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      75532403..75545055
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511431.2 → XP_006511494.1  lysM and putative peptidoglycan-binding domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006511494.1

      UniProtKB/Swiss-Prot
      Q9D7V2

    RNA

    1. XR_003948002.1 RNA Sequence

    2. XR_001779008.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D7V2.2 GenPept UniProtKB/Swiss-Prot:Q9D7V2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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