Mcts2 malignant T cell amplified sequence 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mcts2provided by MGI
Official Full Name: malignant T cell amplified sequence 2provided by MGI
Primary source: MGI:MGI:1913655
See related: Ensembl:ENSMUSG00000042814 AllianceGenome:MGI:1913655
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MCT-2; 2400002F11Rik
Summary: Predicted to enable RNA binding activity. Predicted to be involved in IRES-dependent viral translational initiation; formation of translation preinitiation complex; and ribosome disassembly. Predicted to be located in cytosol and plasma membrane. Predicted to be part of cytosolic small ribosomal subunit. Orthologous to several human genes including MCTS1 (MCTS1 re-initiation and release factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 2 H1; 2 75.41 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (152529091..152529871)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (152687148..152687946)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in formation of translation preinitiation complex	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: malignant T-cell-amplified sequence 2

Names: multiple copies T-cell malignancies 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_025543.3 → NP_079819.1 malignant T-cell-amplified sequence 2

Status: VALIDATED

Source sequence(s)

AL845162

Consensus CDS

CCDS38281.1

UniProtKB/Swiss-Prot

Q9CQ21

Related

ENSMUSP00000100534.3, ENSMUST00000062148.9

Conserved Domains (2) summary

cd11609
Location:4 → 80

MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins

cd21155
Location:80 → 175

PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins