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    Shisal1 shisa like 1 [ Mus musculus (house mouse) ]

    Gene ID: 72301, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Shisal1provided by MGI
    Official Full Name
    shisa like 1provided by MGI
    Primary source
    MGI:MGI:1919551
    See related
    Ensembl:ENSMUSG00000062760 AllianceGenome:MGI:1919551
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kiaa1644; 1810041L15Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; dorsal root ganglion; olfactory epithelium; and retina. Orthologous to human SHISAL1 (shisa like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in bladder adult (RPKM 26.9), frontal lobe adult (RPKM 8.1) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Shisal1 in Genome Data Viewer
    Location:
    15 E2; 15 39.78 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (84263404..84367061, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (84379203..84482860, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene parvin, gamma Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:84185775-84185884 Neighboring gene N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:84214597-84214798 Neighboring gene STARR-seq mESC enhancer starr_39362 Neighboring gene predicted gene, 46527 Neighboring gene STARR-seq mESC enhancer starr_39363 Neighboring gene predicted gene, 33830 Neighboring gene STARR-seq mESC enhancer starr_39364 Neighboring gene STARR-seq mESC enhancer starr_39365 Neighboring gene predicted gene, 33966 Neighboring gene STARR-seq mESC enhancer starr_39367 Neighboring gene predicted gene, 34027

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Mu X, et al. Development, 2004 Mar. PMID 14973295
    2. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
    3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • 1810041L15Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein shisa-like-1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163145.2 → NP_001156617.2  protein shisa-like-1 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
      Source sequence(s)
      AI415268, AK162836, BC062953
      Consensus CDS
      CCDS49687.1
      UniProtKB/Swiss-Prot
      Q0VBP7, Q6P5D2, Q6ZPK6
      Related
      ENSMUSP00000079575.4, ENSMUST00000080751.10
      Conserved Domains (1) summary
      pfam13908
      Location:30 → 70
      Shisa; Wnt and FGF inhibitory regulator

    2. NM_001347543.2 → NP_001334472.1  protein shisa-like-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL603714
      Consensus CDS
      CCDS84184.1
      UniProtKB/TrEMBL
      A0A087WSN1
      Related
      ENSMUSP00000141117.2, ENSMUST00000189248.7
      Conserved Domains (1) summary
      pfam13908
      Location:51 → 91
      Shisa; Wnt and FGF inhibitory regulator

    3. NM_001374162.1 → NP_001361091.1  protein shisa-like-1 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
      Source sequence(s)
      AL603714
      UniProtKB/Swiss-Prot
      Q0VBP7, Q6P5D2, Q6ZPK6
      Conserved Domains (1) summary
      pfam13908
      Location:30 → 70
      Shisa; Wnt and FGF inhibitory regulator

    4. NM_001374163.1 → NP_001361092.1  protein shisa-like-1 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
      Source sequence(s)
      AL603714
      UniProtKB/Swiss-Prot
      Q0VBP7, Q6P5D2, Q6ZPK6
      Conserved Domains (1) summary
      pfam13908
      Location:30 → 70
      Shisa; Wnt and FGF inhibitory regulator

    5. NM_001374164.1 → NP_001361093.1  protein shisa-like-1 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: Variants 1, 3, 4 and 5 encode the same isoform (1).
      Source sequence(s)
      AL603714
      UniProtKB/Swiss-Prot
      Q0VBP7, Q6P5D2, Q6ZPK6
      Conserved Domains (1) summary
      pfam13908
      Location:30 → 70
      Shisa; Wnt and FGF inhibitory regulator

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      84263404..84367061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521445.4 → XP_006521508.1  protein shisa-like-1 isoform X1

      See identical proteins and their annotated locations for XP_006521508.1

      UniProtKB/TrEMBL
      H7BX53
      Conserved Domains (1) summary
      pfam13908
      Location:31 → 71
      Shisa; Wnt and FGF inhibitory regulator

    2. XM_006521443.5 → XP_006521506.1  protein shisa-like-1 isoform X1

      See identical proteins and their annotated locations for XP_006521506.1

      UniProtKB/TrEMBL
      H7BX53
      Conserved Domains (1) summary
      pfam13908
      Location:31 → 71
      Shisa; Wnt and FGF inhibitory regulator
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VBP7.1 GenPept UniProtKB/Swiss-Prot:Q0VBP7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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