Hdhd3 haloacid dehalogenase-like hydrolase domain containing 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Hdhd3provided by MGI
Official Full Name: haloacid dehalogenase-like hydrolase domain containing 3provided by MGI
Primary source: MGI:MGI:1919998
See related: Ensembl:ENSMUSG00000038422 AllianceGenome:MGI:1919998
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2810435D12Rik
Summary: Predicted to enable hydrolase activity. Located in mitochondrion. Orthologous to human HDHD3 (haloacid dehalogenase like hydrolase domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in large intestine adult (RPKM 5.8), duodenum adult (RPKM 4.5) and 17 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 B3; 4 33.16 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (62417291..62420437, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (62499054..62502200, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	HDA more info	PubMed
located_in nucleolus	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: haloacid dehalogenase-like hydrolase domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_024257.1 → NP_077219.1 haloacid dehalogenase-like hydrolase domain-containing protein 3

See identical proteins and their annotated locations for NP_077219.1

Status: PROVISIONAL

Source sequence(s)

BC003491

Consensus CDS

CCDS18242.1

UniProtKB/Swiss-Prot

Q9CYW4

Related

ENSMUSP00000036337.3, ENSMUST00000037820.3

Conserved Domains (2) summary

cd01427
Location:102 → 211

HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...

TIGR02252
Location:8 → 210

DREG-2; REG-2-like, HAD superfamily (subfamily IA) hydrolase