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    Tmbim7 transmembrane BAX inhibitor motif containing 7 [ Mus musculus (house mouse) ]

    Gene ID: 75010, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Tmbim7provided by MGI
    Official Full Name
    transmembrane BAX inhibitor motif containing 7provided by MGI
    Primary source
    MGI:MGI:1922305
    See related
    Ensembl:ENSMUSG00000014529 AllianceGenome:MGI:1922305
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lfg5; Lgf5; Tmbim1b; 4930403J02Rik; 4930500J03Rik; 4930511M11Rik
    Summary
    Is expressed in ductus deferens; epididymis; ileum; prostate gland; and testis. Orthologous to human TMBIM7P (transmembrane BAX inhibitor motif containing 7, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 33.5) See more
    Orthologs
    rat all
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    Genomic context

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    See Tmbim7 in Genome Data Viewer
    Location:
    5 A1; 5 2.26 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (3707004..3729865)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (3657004..3679865)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E429 Neighboring gene RNA binding motif protein 48 Neighboring gene peroxisomal biogenesis factor 1 Neighboring gene STARR-seq mESC enhancer starr_12316 Neighboring gene GATA zinc finger domain containing 1 Neighboring gene predicted gene, 50624 Neighboring gene STARR-seq mESC enhancer starr_12317 Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E4742 Neighboring gene STARR-seq mESC enhancer starr_12318 Neighboring gene KRIT1, ankyrin repeat containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    bax inhibitor 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029141.4 → NP_083417.1  bax inhibitor 1-like isoform b

      See identical proteins and their annotated locations for NP_083417.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform b which is shorter than isoform a.
      Source sequence(s)
      AC022236, AC090443
      Consensus CDS
      CCDS19067.1
      UniProtKB/TrEMBL
      Q9D592
      Related
      ENSMUSP00000014673.3, ENSMUST00000014673.9
      Conserved Domains (1) summary
      cd10428
      Location:84 → 301
      LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

    2. NM_029154.1 → NP_083430.1  bax inhibitor 1-like isoform a

      See identical proteins and their annotated locations for NP_083430.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC022236, AC090443, AK015761
      Consensus CDS
      CCDS80202.1
      UniProtKB/TrEMBL
      Q9D561
      Related
      ENSMUSP00000143399.2, ENSMUST00000198739.5
      Conserved Domains (1) summary
      cd10428
      Location:28 → 223
      LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      3707004..3729865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503611.4 → XP_006503674.1  bax inhibitor 1-like isoform X1

      Conserved Domains (1) summary
      cd10428
      Location:84 → 287
      LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

    2. XM_006503614.4 → XP_006503677.1  bax inhibitor 1-like isoform X4

      Conserved Domains (1) summary
      cl00473
      Location:84 → 137
      BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family

    3. XM_017321125.2 → XP_017176614.1  bax inhibitor 1-like isoform X3

      UniProtKB/TrEMBL
      F7AB47
      Related
      ENSMUSP00000117435.2, ENSMUST00000156117.2
      Conserved Domains (1) summary
      cl00473
      Location:84 → 241
      BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family

    4. XM_006503612.4 → XP_006503675.1  bax inhibitor 1-like isoform X2

      UniProtKB/TrEMBL
      F7AB47
      Conserved Domains (1) summary
      cl00473
      Location:84 → 255
      BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family

    5. XM_030254863.1 → XP_030110723.1  bax inhibitor 1-like isoform X5

      Conserved Domains (1) summary
      cl00473
      Location:1 → 160
      BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family
    Nucleotide Protein Strain
    Heading Accession and Version

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