psmd6 proteasome 26S subunit, non-ATPase 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmd6provided by ZNC
Official Full Name: proteasome 26S subunit, non-ATPase 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1038
See related: Ensembl:ENSDARG00000070674 AllianceGenome:ZFIN:ZDB-GENE-040426-1038
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56471
Summary: Predicted to enable enzyme regulator activity. Acts upstream of or within lens fiber cell differentiation and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle. Is expressed in ciliary marginal zone; head; and lens epithelium. Orthologous to human PSMD6 (proteasome 26S subunit, non-ATPase 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (19502367..19511548)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (19340025..19349206)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within lens fiber cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteasome-mediated ubiquitin-dependent protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 6

Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 6; vov

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200291.1 → NP_956585.1 26S proteasome non-ATPase regulatory subunit 6

See identical proteins and their annotated locations for NP_956585.1

Status: PROVISIONAL

Source sequence(s)

BC049452

UniProtKB/TrEMBL

Q7ZWE5

Related

ENSDARP00000094762.2, ENSDART00000103987.3

Conserved Domains (3) summary

COG5187
Location:15 → 379

RPN7; 26S proteasome regulatory complex component, contains PCI domain [Posttranslational modification, protein turnover, chaperones]

pfam01399
Location:251 → 355

PCI; PCI domain

pfam10602
Location:63 → 236

RPN7; 26S proteasome subunit RPN7