Mrps9 mitochondrial ribosomal protein S9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mrps9provided by MGI
Official Full Name: mitochondrial ribosomal protein S9provided by MGI
Primary source: MGI:MGI:1916777
See related: Ensembl:ENSMUSG00000060679 AllianceGenome:MGI:1916777
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: S9mt; mg637; Mrp-S9; 2310002A08Rik
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; gonad; liver; and thymus primordium. Orthologous to human MRPS9 (mitochondrial ribosomal protein S9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 11.2), heart adult (RPKM 8.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 B; 1 21.62 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (42890393..42944843)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (42851233..42905683)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MRPS9-Mediated Regulation of the PI3K/Akt/mTOR Pathway Inhibits Neuron Apoptosis and Protects Ischemic Stroke.
Title: MRPS9-Mediated Regulation of the PI3K/Akt/mTOR Pathway Inhibits Neuron Apoptosis and Protects Ischemic Stroke.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:488799

AW322516 (e-PCR)
- UniSTS:178384

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mitochondrial translation	NAS Non-traceable Author Statement more info	PubMed
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	NAS Non-traceable Author Statement more info	PubMed
part_of mitochondrial small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial small ribosomal subunit	NAS Non-traceable Author Statement more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: small ribosomal subunit protein uS9m

Names: 28S ribosomal protein S9, mitochondrial; muscle protein 637

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_023514.4 → NP_076003.3 small ribosomal subunit protein uS9m precursor

See identical proteins and their annotated locations for NP_076003.3

Status: VALIDATED

Source sequence(s)

BC051936, BC116437, BY145802

Consensus CDS

CCDS14918.1

UniProtKB/Swiss-Prot

Q14AZ3, Q6IS29, Q80W17, Q9D7N3

UniProtKB/TrEMBL

A0A1S6GWG5

Related

ENSMUSP00000056855.9, ENSMUST00000057208.13

Conserved Domains (1) summary

pfam00380
Location:268 → 390

Ribosomal_S9; Ribosomal protein S9/S16

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000067.7 Reference GRCm39 C57BL/6J

Range

42890393..42944843

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030242824.1 → XP_030098684.1 small ribosomal subunit protein uS9m isoform X1

UniProtKB/TrEMBL

Q9ER89

Conserved Domains (1) summary

pfam00380
Location:107 → 229

Ribosomal_S9; Ribosomal protein S9/S16
XM_036153502.1 → XP_036009395.1 small ribosomal subunit protein uS9m isoform X1

UniProtKB/TrEMBL

Q9ER89

Conserved Domains (1) summary

pfam00380
Location:107 → 229

Ribosomal_S9; Ribosomal protein S9/S16