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    Fam110b family with sequence similarity 110, member B [ Mus musculus (house mouse) ]

    Gene ID: 242297, updated on 12-May-2024

    Summary

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    Official Symbol
    Fam110bprovided by MGI
    Official Full Name
    family with sequence similarity 110, member Bprovided by MGI
    Primary source
    MGI:MGI:1916593
    See related
    Ensembl:ENSMUSG00000049119 AllianceGenome:MGI:1916593
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5031405P22; 1700012H17Rik
    Summary
    Predicted to be located in cytosol and mitochondrion. Orthologous to human FAM110B (family with sequence similarity 110 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 18.0), whole brain E14.5 (RPKM 14.4) and 21 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam110b in Genome Data Viewer
    Location:
    4 A1; 4 2.62 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (5644009..5801101)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (5644009..5801101)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09455 Neighboring gene family with sequence similarity 20, member B pseudogene Neighboring gene STARR-seq mESC enhancer starr_09456 Neighboring gene STARR-seq mESC enhancer starr_09457 Neighboring gene STARR-seq mESC enhancer starr_09458 Neighboring gene STARR-seq mESC enhancer starr_09459 Neighboring gene STARR-seq mESC enhancer starr_09460 Neighboring gene STARR-seq mESC enhancer starr_09461 Neighboring gene STARR-seq mESC enhancer starr_09463 Neighboring gene RIKEN cDNA 4930423M02 gene Neighboring gene STARR-seq mESC enhancer starr_09464 Neighboring gene STARR-seq mESC enhancer starr_09467 Neighboring gene STARR-seq mESC enhancer starr_09468 Neighboring gene STARR-seq mESC enhancer starr_09469 Neighboring gene predicted gene, 24337 Neighboring gene VISTA enhancer mm718 Neighboring gene STARR-seq mESC enhancer starr_09473 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene zinc finger protein 46 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM110B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355716.1 → NP_001342645.1  protein FAM110B

      Status: VALIDATED

      Source sequence(s)
      AK049898, AW049855, BC055683, BY292674
      Consensus CDS
      CCDS17948.1
      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Related
      ENSMUSP00000104017.2, ENSMUST00000108380.2
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    2. NM_173426.3 → NP_775602.1  protein FAM110B

      See identical proteins and their annotated locations for NP_775602.1

      Status: VALIDATED

      Source sequence(s)
      AK049898, AK052596, AK080588, AL772304, AW049855, BY269222
      Consensus CDS
      CCDS17948.1
      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Related
      ENSMUSP00000062734.7, ENSMUST00000054857.13
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      5644009..5801101
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537896.4 → XP_006537959.1  protein FAM110B isoform X1

      See identical proteins and their annotated locations for XP_006537959.1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    2. XM_030253522.2 → XP_030109382.1  protein FAM110B isoform X1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    3. XM_030253518.2 → XP_030109378.1  protein FAM110B isoform X1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    4. XM_030253519.1 → XP_030109379.1  protein FAM110B isoform X1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    5. XM_030253523.1 → XP_030109383.1  protein FAM110B isoform X1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    6. XM_030253520.1 → XP_030109380.1  protein FAM110B isoform X1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    7. XM_006537897.1 → XP_006537960.1  protein FAM110B isoform X1

      See identical proteins and their annotated locations for XP_006537960.1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Related
      ENSMUSP00000127942.2, ENSMUST00000171403.2
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus

    8. XM_006537898.5 → XP_006537961.1  protein FAM110B isoform X1

      See identical proteins and their annotated locations for XP_006537961.1

      UniProtKB/Swiss-Prot
      Q3UKH0, Q8C739
      Conserved Domains (2) summary
      pfam14160
      Location:249 → 357
      FAM110_C; Centrosome-associated C-terminus
      pfam14161
      Location:17 → 118
      FAM110_N; Centrosome-associated N-terminus
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C739.1 GenPept UniProtKB/Swiss-Prot:Q8C739

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