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    Coa7 cytochrome c oxidase assembly factor 7 [ Mus musculus (house mouse) ]

    Gene ID: 69893, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Coa7provided by MGI
    Official Full Name
    cytochrome c oxidase assembly factor 7provided by MGI
    Primary source
    MGI:MGI:1917143
    See related
    Ensembl:ENSMUSG00000048351 AllianceGenome:MGI:1917143
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Selrc1; D4Ertd796e; 2010305A19Rik
    Summary
    Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in mitochondrial intermembrane space. Orthologous to human COA7 (cytochrome c oxidase assembly factor 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.5), placenta adult (RPKM 5.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Coa7 in Genome Data Viewer
    Location:
    4 C7; 4 50.44 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108185349..108197915)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108328152..108340718)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zyg-11 family member A, cell cycle regulator Neighboring gene STARR-seq mESC enhancer starr_11034 Neighboring gene predicted gene, 54249 Neighboring gene zyg-ll family member B, cell cycle regulator Neighboring gene STARR-positive B cell enhancer ABC_E2701 Neighboring gene STARR-seq mESC enhancer starr_11037 Neighboring gene STARR-seq mESC enhancer starr_11038 Neighboring gene STARR-positive B cell enhancer ABC_E11249 Neighboring gene STARR-positive B cell enhancer ABC_E10246 Neighboring gene STARR-positive B cell enhancer ABC_E7979 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:108000774-108000883 Neighboring gene STARR-positive B cell enhancer ABC_E2702 Neighboring gene predicted gene, 46889 Neighboring gene VISTA enhancer mm1490 Neighboring gene predicted gene, 54250 Neighboring gene shisa like 2A Neighboring gene predicted gene, 32297

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. C1orf163/RESA1 is a novel mitochondrial intermembrane space protein connected to respiratory chain assembly. Kozjak-Pavlovic V, et al. J Mol Biol, 2014 Feb 20. PMID 24333015
    2. The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue. Martins-de-Souza D, et al. Proteomics Clin Appl, 2015 Oct. PMID 25921334
    3. Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Kim SC, et al. Mol Cell, 2006 Aug. PMID 16916647
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome c oxidase assembly factor 7
    Names
    Sel1 repeat containing 1
    beta-lactamase hcp-like protein
    hcp beta-lactamase-like protein C1orf163 homolog
    respiratory chain assembly factor 1
    sel1 repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027250.4 → NP_081526.1  cytochrome c oxidase assembly factor 7

      See identical proteins and their annotated locations for NP_081526.1

      Status: PROVISIONAL

      Source sequence(s)
      AL627238
      Consensus CDS
      CCDS18449.1
      UniProtKB/Swiss-Prot
      Q921H9
      Related
      ENSMUSP00000114906.2, ENSMUST00000131656.2
      Conserved Domains (2) summary
      COG0790
      Location:30 → 218
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:50 → 80
      SLR; SLR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      108185349..108197915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q921H9.1 GenPept UniProtKB/Swiss-Prot:Q921H9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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