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    Ccdc187 coiled-coil domain containing 187 [ Mus musculus (house mouse) ]

    Gene ID: 329366, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Ccdc187provided by MGI
    Official Full Name
    coiled-coil domain containing 187provided by MGI
    Primary source
    MGI:MGI:3045295
    See related
    Ensembl:ENSMUSG00000048038 AllianceGenome:MGI:3045295
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932418E24Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in microtubule anchoring. Predicted to be located in centrosome. Is expressed in brain ventricle and choroid plexus and nose. Orthologous to human CCDC187 (coiled-coil domain containing 187). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 12.3), genital fat pad adult (RPKM 2.8) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc187 in Genome Data Viewer
    Location:
    2 A3; 2 18.54 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26161659..26184569, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26243449..26300204, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_03977 Neighboring gene quiescin Q6 sulfhydryl oxidase 2 Neighboring gene STARR-positive B cell enhancer ABC_E10086 Neighboring gene STARR-seq mESC enhancer starr_03978 Neighboring gene predicted gene, 52504 Neighboring gene predicted gene, 35807 Neighboring gene STARR-seq mESC enhancer starr_03980 Neighboring gene predicted gene, 52505 Neighboring gene G-protein signalling modulator 1 (AGS3-like, C. elegans) Neighboring gene predicted gene 13562 Neighboring gene DNL-type zinc finger

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in microtubule anchoring IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 187

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001428391.1 → NP_001415320.1  coiled-coil domain-containing protein 187 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL773595
      UniProtKB/TrEMBL
      A0A1L1SUD9

    2. NM_001428392.1 → NP_001415321.1  coiled-coil domain-containing protein 187 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL773595
      UniProtKB/TrEMBL
      A0A1L1SUD9, A0A2I3BPI0

    3. NM_177841.4 → NP_808509.1  coiled-coil domain-containing protein 187 isoform 3

      See identical proteins and their annotated locations for NP_808509.1

      Status: VALIDATED

      Source sequence(s)
      AL773595
      Consensus CDS
      CCDS50539.1
      UniProtKB/Swiss-Prot
      Q8C5V8
      Related
      ENSMUSP00000054283.4, ENSMUST00000057224.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      26161659..26184569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C5V8.1 GenPept UniProtKB/Swiss-Prot:Q8C5V8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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