U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mRpL43 mitochondrial ribosomal protein L43 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37750, updated on 10-May-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mRpL43provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L43provided by FlyBase
    Primary source
    FLYBASE:FBgn0034893
    Locus tag
    Dmel_CG5479
    See related
    AllianceGenome:FB:FBgn0034893
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE35686; CG5479; CI-B8; Dmel\CG5479; mRpL-CI-B8; mRPL43
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including adult heart; early extended germ band embryo; embryonic/larval muscle system; gut section; and presumptive embryonic/larval digestive system. Orthologous to human MRPL43 (mitochondrial ribosomal protein L43). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mRpL43 in Genome Data Viewer
    Location:
    59F6-59F6; 2-104 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23698105..23699014)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19585628..19586537)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2 Neighboring gene uncharacterized protein Neighboring gene angel Neighboring gene salivary glands marred Neighboring gene lethal-(2)-denticleless Neighboring gene ALG3, alpha-1,3- mannosyltransferase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis. Melvin RG, et al. Elife, 2018 Nov 27. PMID 30480548, Free PMC Article
    2. Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. Aspden JL, et al. Elife, 2014 Aug 21. PMID 25144939, Free PMC Article
    3. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
    4. The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication. Zhang Y, et al. EMBO J, 2016 May 17. PMID 27053724, Free PMC Article
    5. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    mitochondrial ribosomal protein L43
    Names
    CG5479-PA
    mRpL43-PA
    mitochondrial ribosomal protein L-CI-B8

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23698105..23699014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079104.3 → NP_523828.1  mitochondrial ribosomal protein L43 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523828.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1L1
      Related
      FBpp0071993
      Conserved Domains (1) summary
      smart00916
      Location:40 → 109
      L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1L1 Q9W1L1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous