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    sfxn-1.4 Sideroflexin-2;Sidoreflexin [ Caenorhabditis elegans ]

    Gene ID: 183547, updated on 25-Apr-2024

    Summary

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    Gene symbol
    sfxn-1.4
    Gene description
    Sideroflexin-2;Sidoreflexin
    Primary source
    WormBase:WBGene00008137
    Locus tag
    CELE_C47D12.3
    See related
    AllianceGenome:WB:WBGene00008137
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Predicted to be integral component of membrane. Predicted to be integral component of mitochondrial inner membrane. Orthologous to human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See sfxn-1.4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (11679091..11681236, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transcription-associated protein 1 Neighboring gene Dymeclin Neighboring gene F-box domain-containing protein Neighboring gene CUB domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables monoatomic ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in serine import into mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sideroflexin-2;Sidoreflexin
    NP_001254308.1
    • Confirmed by transcript evidence
    NP_001379510.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11679091..11681236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267379.4 → NP_001254308.1  Sidoreflexin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254308.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18666
      Conserved Domains (1) summary
      TIGR00798
      Location:13 → 326
      mtc; tricarboxylate carrier

    2. NM_001393201.1 → NP_001379510.1  Sideroflexin-2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3KFU4
      Conserved Domains (1) summary
      cl04275
      Location:1 → 156
      Mtc; Tricarboxylate carrier
    Nucleotide Protein
    Heading Accession and Version

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