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    Fam98c family with sequence similarity 98, member C [ Mus musculus (house mouse) ]

    Gene ID: 73833, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam98cprovided by MGI
    Official Full Name
    family with sequence similarity 98, member Cprovided by MGI
    Primary source
    MGI:MGI:1921083
    See related
    Ensembl:ENSMUSG00000030590 AllianceGenome:MGI:1921083
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110006G06Rik; B230110F21Rik
    Summary
    Predicted to be part of tRNA-splicing ligase complex. Orthologous to human FAM98C (family with sequence similarity 98 member C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in duodenum adult (RPKM 77.5), testis adult (RPKM 67.6) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 B1; 7 16.94 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28851935..28855653, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29152510..29157104, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ryanodine receptor 1, skeletal muscle Neighboring gene predicted gene, 26604 Neighboring gene STARR-seq mESC enhancer starr_18458 Neighboring gene microRNA 1963 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29926525-29926755 Neighboring gene RAS guanyl releasing protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E9287 Neighboring gene STARR-positive B cell enhancer ABC_E8159 Neighboring gene sprouty-related EVH1 domain containing 3 Neighboring gene gametogenetin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of tRNA-splicing ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM98C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001146023.1 → NP_001139495.1  protein FAM98C

      Status: PROVISIONAL

      Source sequence(s)
      AI836081, AK138395, BY237292
      Consensus CDS
      CCDS52167.1
      UniProtKB/TrEMBL
      E9PYD1
      Related
      ENSMUSP00000131477.2, ENSMUST00000164589.9
      Conserved Domains (1) summary
      pfam10239
      Location:10 → 325
      DUF2465; Protein of unknown function (DUF2465)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28851935..28855653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540393.5 → XP_006540456.1  protein FAM98C isoform X1

      Conserved Domains (1) summary
      pfam10239
      Location:10 → 288
      DUF2465; Protein of unknown function (DUF2465)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_028661.2: Suppressed sequence

      Description
      NM_028661.2: This RefSeq was permanently suppressed because it contains the wrong CDS.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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