rps-3 Small ribosomal subunit protein uS3 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: rps-3
Gene description: Small ribosomal subunit protein uS3
Primary source: WormBase:WBGene00004472
Locus tag: CELE_C23G10.3
See related: AllianceGenome:WB:WBGene00004472
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of apoptotic signaling pathway. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in nucleus. Orthologous to human RPS3 (ribosomal protein S3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See rps-3 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 5

Sequence:: Chromosome: III; NC_003281.10 (6206803..6207965)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C23G10.3 (e-PCR)
- UniSTS:306971

C23G10.9 (e-PCR)
- UniSTS:320466

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosolic ribosome	IEA Inferred from Electronic Annotation more info
part_of cytosolic small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info
part_of small ribosomal subunit	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Small ribosomal subunit protein uS3

NP_498349.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

6206803..6207965

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065948.6 → NP_498349.1 Small ribosomal subunit protein uS3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498349.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P48152

Conserved Domains (3) summary

cd02413
Location:17 → 97

40S_S3_KH; K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3 is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH ...

PTZ00084
Location:5 → 218

PTZ00084; 40S ribosomal protein S3; Provisional

pfam00189
Location:107 → 188

Ribosomal_S3_C; Ribosomal protein S3, C-terminal domain