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    Rex1bd required for excision 1-B domain containing [ Mus musculus (house mouse) ]

    Gene ID: 66462, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Rex1bdprovided by MGI
    Official Full Name
    required for excision 1-B domain containingprovided by MGI
    Primary source
    MGI:MGI:1913712
    See related
    Ensembl:ENSMUSG00000058833 AllianceGenome:MGI:1913712
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810428I15Rik
    Summary
    Orthologous to human REX1BD (required for excision 1-B domain containing). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 105.5), ovary adult (RPKM 88.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rex1bd in Genome Data Viewer
    Location:
    8 B3.3; 8 34.15 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70956945..70959402, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70504295..70506752, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700020G03 gene Neighboring gene cytokine receptor-like factor 1 Neighboring gene RIKEN cDNA 4930522P08 gene Neighboring gene STARR-positive B cell enhancer ABC_E5013 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    required for excision 1-B domain-containing protein
    Names
    uncharacterized protein C19orf60 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357209.1 → NP_001344138.1  required for excision 1-B domain-containing protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AA217756, AC157774, AK013181, BX526270
      Conserved Domains (1) summary
      pfam14966
      Location:31 → 118
      DNA_repr_REX1B; DNA repair REX1-B

    2. NM_025577.3 → NP_079853.1  required for excision 1-B domain-containing protein isoform 1

      See identical proteins and their annotated locations for NP_079853.1

      Status: VALIDATED

      Source sequence(s)
      AA217756, AC157774, AK013181
      Consensus CDS
      CCDS22370.1
      UniProtKB/Swiss-Prot
      Q3TUY7, Q9CRH2, Q9CYZ6
      UniProtKB/TrEMBL
      D3YZ60
      Related
      ENSMUSP00000074670.6, ENSMUST00000075175.12
      Conserved Domains (1) summary
      pfam14966
      Location:31 → 126
      DNA_repr_REX1B; DNA repair REX1-B

    RNA

    1. NR_151646.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA217756, AC157774, BQ747525, BY285907
      Related
      ENSMUST00000133683.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      70956945..70959402 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CYZ6.1 GenPept UniProtKB/Swiss-Prot:Q9CYZ6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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