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    myo15b myosin XVB [ Danio rerio (zebrafish) ]

    Gene ID: 795537, updated on 27-Mar-2024

    Summary

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    Official Symbol
    myo15bprovided by ZNC
    Official Full Name
    myosin XVBprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4797
    See related
    Ensembl:ENSDARG00000074852 AllianceGenome:ZFIN:ZDB-GENE-030131-4797
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fd60h05; si:dkeyp-67e6.5
    Summary
    Located in cytoplasm and nucleus. Orthologous to human MYO15B (myosin XVB). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See myo15b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (33661649..33714846, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (33560666..33608405, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene tudor and KH domain containing Neighboring gene transmembrane protein 94 Neighboring gene E3 ubiquitin-protein ligase RBBP6-like Neighboring gene LLGL scribble cell polarity complex component 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Choksi SP, et al. Development, 2014 Sep. PMID 25139857, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin XVB

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      33661649..33714846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017358549.2 → XP_017214038.2  myosin XVB

      UniProtKB/TrEMBL
      A0A8M6Z8Z4
      Related
      ENSDARP00000127409.1, ENSDART00000153135.3
      Conserved Domains (8) summary
      cd13201
      Location:1787 → 1887
      FERM_C_MyoXV; FERM domain C-lobe of Myosin XV (MyoXV/Myo15)
      pfam00612
      Location:221 → 241
      IQ; IQ calmodulin-binding motif
      pfam00784
      Location:1476 → 1581
      MyTH4; MyTH4 domain
      cl02480
      Location:359 → 503
      MyTH4; MyTH4 domain
      cl09511
      Location:1590 → 1791
      FERM_B-lobe; FERM domain B-lobe
      cl17036
      Location:1262 → 1316
      SH3; Src Homology 3 domain superfamily
      cl22853
      Location:5 → 182
      Motor_domain; Myosin and Kinesin motor domain
      cl25800
      Location:812 → 962
      GGN; Gametogenetin

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394855.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      252915..305917 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472579.1 → XP_021328254.1  myosin XVB

      UniProtKB/TrEMBL
      A0A8M9PTM5
      Conserved Domains (8) summary
      cd13201
      Location:1787 → 1887
      FERM_C_MyoXV; FERM domain C-lobe of Myosin XV (MyoXV/Myo15)
      pfam00612
      Location:221 → 241
      IQ; IQ calmodulin-binding motif
      pfam00784
      Location:1476 → 1581
      MyTH4; MyTH4 domain
      cl02480
      Location:359 → 503
      MyTH4; MyTH4 domain
      cl09511
      Location:1590 → 1791
      FERM_B-lobe; FERM domain B-lobe
      cl17036
      Location:1262 → 1316
      SH3; Src Homology 3 domain superfamily
      cl22853
      Location:5 → 182
      Motor_domain; Myosin and Kinesin motor domain
      cl26464
      Location:818 → 955
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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