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    ppt2a.3 palmitoyl-protein thioesterase 2a, tandem duplicate 3 [ Danio rerio (zebrafish) ]

    Gene ID: 406830, updated on 25-Apr-2024

    Summary

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    Official Symbol
    ppt2a.3provided by ZNC
    Official Full Name
    palmitoyl-protein thioesterase 2a, tandem duplicate 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2909
    See related
    Ensembl:ENSDARG00000014208 AllianceGenome:ZFIN:ZDB-GENE-040426-2909
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55413; wu:fc23c11; wu:fi06h07
    Summary
    Predicted to enable thiolester hydrolase activity. Predicted to be active in lysosome. Orthologous to human PPT2 (palmitoyl-protein thioesterase 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ppt2a.3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (35102458..35112949, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (35244489..35254980, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene sestrin 3 Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 3 Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 4 Neighboring gene serine/threonine-protein kinase pim-2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Gonad differentiation in zebrafish is regulated by the canonical Wnt signaling pathway. Sreenivasan R, et al. Biol Reprod, 2014 Feb. PMID 24174574
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiolester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC406830

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001309531.1 → NP_001296460.1  uncharacterized protein LOC406830 precursor

      Status: VALIDATED

      Source sequence(s)
      CR387932, EH491109
      UniProtKB/TrEMBL
      A0A8M1P7P7, E7FC96
      Related
      ENSDARP00000090416.3, ENSDART00000099642.3
      Conserved Domains (1) summary
      cl21494
      Location:27 → 260
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      35102458..35112949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_213509.1: Suppressed sequence

      Description
      NM_213509.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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