acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: acap1provided by ZNC
Official Full Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-1242
See related: Ensembl:ENSDARG00000056346 AllianceGenome:ZFIN:ZDB-GENE-070112-1242
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Cnt-b1; centb1; zgc:153917
Summary: Predicted to enable GTPase activator activity and metal ion binding activity. Is expressed in intestine. Orthologous to human ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (20058857..20103332, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (19806889..19851364, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in endosome membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080579.1 → NP_001074048.1 arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

See identical proteins and their annotated locations for NP_001074048.1

Status: PROVISIONAL

Source sequence(s)

BC129036

UniProtKB/TrEMBL

A0A8M1NBL4, A1L1F5

Related

ENSDARP00000052901.6, ENSDART00000052902.9

Conserved Domains (7) summary

cd00204
Location:583 → 709

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd13250
Location:269 → 365

PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain

pfam00169
Location:269 → 361

PH; PH domain

pfam01412
Location:398 → 516

ArfGap; Putative GTPase activating protein for Arf

pfam12796
Location:593 → 687

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:623 → 654

ANK; ANK repeat [structural motif]

cl12013
Location:18 → 217

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature