klc1b kinesin light chain 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: klc1bprovided by ZNC
Official Full Name: kinesin light chain 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7439
See related: AllianceGenome:ZFIN:ZDB-GENE-030131-7439
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Klc2; klc1; kns2; zgc:55666; zgc:77660; wu:fj17e04
Summary: Predicted to be located in cytoplasm and microtubule. Predicted to be part of kinesin complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Orthologous to human KLC1 (kinesin light chain 1). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (51903588..52169179)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (51518774..51530158)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

z99040 (e-PCR), detects polymorphism
- UniSTS:238600

fi77g03.y1 (e-PCR)
- UniSTS:198040

AW184674 (e-PCR)
- UniSTS:205745

Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
part_of kinesin complex	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: kinesin light chain 1b

Names: kinesin 2; kinesin light chain 1; kinesin light chain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199954.1 → NP_956248.1 kinesin light chain 1b

See identical proteins and their annotated locations for NP_956248.1

Status: PROVISIONAL

Source sequence(s)

BC063959

UniProtKB/TrEMBL

Q6P3K1, Q7ZVT4

Conserved Domains (4) summary

sd00006
Location:294 → 322

TPR; TPR repeat [structural motif]

pfam13374
Location:293 → 334

TPR_10; Tetratricopeptide repeat

pfam13424
Location:248 → 326

TPR_12; Tetratricopeptide repeat

cl00388
Location:13 → 70

Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold