chchd6a coiled-coil-helix-coiled-coil-helix domain containing 6a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: chchd6aprovided by ZNC
Official Full Name: coiled-coil-helix-coiled-coil-helix domain containing 6aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040930-2
See related: Ensembl:ENSDARG00000003206 AllianceGenome:ZFIN:ZDB-GENE-040930-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: chchd6; zeh0124; zgc:91802; hm:zeh0124
Summary: Predicted to be involved in cellular response to DNA damage stimulus and cristae formation. Predicted to be located in mitochondrial inner membrane. Predicted to be part of MICOS complex. Orthologous to human CHCHD6 (coiled-coil-helix-coiled-coil-helix domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (34047364..34185019)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (34120832..34258488)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in DNA damage response	ISS Inferred from Sequence or Structural Similarity more info
involved_in cristae formation	ISS Inferred from Sequence or Structural Similarity more info
involved_in inner mitochondrial membrane organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of MICOS complex	IBA Inferred from Biological aspect of Ancestor more info
part_of MICOS complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: MICOS complex subunit mic25a

Names: coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005584.1 → NP_001005584.1 MICOS complex subunit mic25a

See identical proteins and their annotated locations for NP_001005584.1

Status: PROVISIONAL

Source sequence(s)

BC082793

UniProtKB/Swiss-Prot

Q63ZW2

Related

ENSDARP00000116560.1, ENSDART00000143933.3

Conserved Domains (2) summary

pfam05300
Location:16 → 187

DUF737; Protein of unknown function (DUF737)

pfam06747
Location:195 → 229

CHCH; CHCH domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

34047364..34185019

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005162311.3 → XP_005162368.1 MICOS complex subunit mic25a isoform X1

UniProtKB/TrEMBL

A0A2U3TWB2, A0A8M6Z3Q6

Conserved Domains (2) summary

pfam05300
Location:16 → 195

DUF737; Protein of unknown function (DUF737)

pfam06747
Location:203 → 237

CHCH; CHCH domain
XM_005162312.2 → XP_005162369.1 MICOS complex subunit mic25a isoform X2

See identical proteins and their annotated locations for XP_005162369.1

UniProtKB/Swiss-Prot

Q63ZW2

Conserved Domains (2) summary

pfam05300
Location:16 → 187

DUF737; Protein of unknown function (DUF737)

pfam06747
Location:195 → 229

CHCH; CHCH domain
XM_017353546.2 → XP_017209035.1 MICOS complex subunit mic25a isoform X1

UniProtKB/TrEMBL

A0A2U3TWB2, A0A8M6Z3Q6

Related

ENSDARP00000143276.2, ENSDART00000176139.2

Conserved Domains (2) summary

pfam05300
Location:16 → 195

DUF737; Protein of unknown function (DUF737)

pfam06747
Location:203 → 237

CHCH; CHCH domain