mrpl18 mitochondrial ribosomal protein L18 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mrpl18provided by ZNC
Official Full Name: mitochondrial ribosomal protein L18provided by ZNC
Primary source: ZFIN:ZDB-GENE-061013-632
See related: Ensembl:ENSDARG00000060199 AllianceGenome:ZFIN:ZDB-GENE-061013-632
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:153420
Summary: Predicted to enable 5S rRNA binding activity. Predicted to act upstream of or within translation. Predicted to be located in ribosome. Predicted to be active in mitochondrion. Orthologous to human MRPL18 (mitochondrial ribosomal protein L18). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (35499678..35505521, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (35159364..35165207, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 5S rRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 39S ribosomal protein L18, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077330.1 → NP_001070798.1 39S ribosomal protein L18, mitochondrial

See identical proteins and their annotated locations for NP_001070798.1

Status: PROVISIONAL

Source sequence(s)

BC124672

UniProtKB/TrEMBL

Q08BK7

Related

ENSDARP00000079005.5, ENSDART00000084570.6

Conserved Domains (1) summary

cd00432
Location:78 → 181

Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007125.7 Reference GRCz11 Primary Assembly

Range

35499678..35505521 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005157321.3 → XP_005157378.1 39S ribosomal protein L18, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A8M2B437, E9QDQ8

Related

ENSDARP00000117764.1, ENSDART00000133658.3

Conserved Domains (1) summary

cd00432
Location:77 → 180

Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...