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    slc30a9 solute carrier family 30 member 9 [ Danio rerio (zebrafish) ]

    Gene ID: 497184, updated on 27-Mar-2024

    Summary

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    Official Symbol
    slc30a9provided by ZNC
    Official Full Name
    solute carrier family 30 member 9provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040724-254
    See related
    Ensembl:ENSDARG00000057272 AllianceGenome:ZFIN:ZDB-GENE-040724-254
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ZnT9; zgc:92098; si:ch211-240l14.4
    Summary
    Predicted to enable nuclear receptor coactivator activity and zinc ion transmembrane transporter activity. Predicted to be involved in cellular zinc ion homeostasis; positive regulation of transcription by RNA polymerase II; and zinc ion transport. Predicted to act upstream of or within cation transport and transmembrane transport. Predicted to be located in cytoplasmic vesicle and endoplasmic reticulum. Predicted to be active in nucleus. Orthologous to human SLC30A9 (solute carrier family 30 member 9). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See slc30a9 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (44804267..44824631)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (44342950..44363318)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene translocase of outer mitochondrial membrane 5 homolog (yeast) Neighboring gene glyoxylate reductase/hydroxypyruvate reductase a Neighboring gene zgc:195212 Neighboring gene glutaredoxin and cysteine rich domain containing 1 a Neighboring gene ATPase phospholipid transporting 8A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model. Beaver LM, et al. J Nutr Biochem, 2017 May. PMID 28268202, Free PMC Article
    2. The involvement of zinc transporters in the zinc accumulation in the Pacific oyster Crassostrea gigas. Kong N, et al. Gene, 2020 Aug 5. PMID 32423892
    3. Zinc transporter expression in zebrafish (Danio rerio) during development. Ho E, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2012 Jan. PMID 21596156, Free PMC Article
    4. The phylogeny of teleost ZIP and ZnT zinc transporters and their tissue specific expression and response to zinc in zebrafish. Feeney GP, et al. Biochim Biophys Acta, 2005 Dec 30. PMID 16500426
    5. Slc39a7/zip7 plays a critical role in development and zinc homeostasis in zebrafish. Yan G, et al. PLoS One, 2012. PMID 22912764, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monoatomic cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular zinc ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular zinc ion homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within monoatomic cation transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mitochondrion organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within zinc ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in zinc ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within zinc ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in zinc ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    proton-coupled zinc antiporter SLC30A9, mitochondrial; zinc transporter 9
    Names
    solute carrier family 30 (zinc transporter), member 9
    znT-9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008575.1 → NP_001008575.1  proton-coupled zinc antiporter SLC30A9, mitochondrial

      See identical proteins and their annotated locations for NP_001008575.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086961
      UniProtKB/Swiss-Prot
      Q5PQZ3, Q7SZY6
      Related
      ENSDARP00000074317.5, ENSDART00000079866.7
      Conserved Domains (4) summary
      TIGR00598
      Location:129 → 219
      rad14; DNA repair protein
      TIGR01297
      Location:259 → 525
      CDF; cation diffusion facilitator family transporter
      pfam01545
      Location:256 → 455
      Cation_efflux; Cation efflux family
      pfam12137
      Location:428 → 573
      RapA_C; RNA polymerase recycling family C-terminal

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      44804267..44824631
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173334.4 → XP_005173391.1  zinc transporter 9 isoform X1

      See identical proteins and their annotated locations for XP_005173391.1

      UniProtKB/Swiss-Prot
      Q5PQZ3, Q7SZY6
      Conserved Domains (4) summary
      TIGR00598
      Location:129 → 219
      rad14; DNA repair protein
      TIGR01297
      Location:259 → 525
      CDF; cation diffusion facilitator family transporter
      pfam01545
      Location:256 → 455
      Cation_efflux; Cation efflux family
      pfam12137
      Location:428 → 573
      RapA_C; RNA polymerase recycling family C-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5PQZ3.1 GenPept UniProtKB/Swiss-Prot:Q5PQZ3

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