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    Rhog ras homolog family member G [ Mus musculus (house mouse) ]

    Gene ID: 56212, updated on 30-Apr-2024

    Summary

    Official Symbol
    Rhogprovided by MGI
    Official Full Name
    ras homolog family member Gprovided by MGI
    Primary source
    MGI:MGI:1928370
    See related
    Ensembl:ENSMUSG00000073982 AllianceGenome:MGI:1928370
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arhg; Sid10750; 2810426G09Rik
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within regulation of ruffle assembly. Predicted to be located in membrane. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Orthologous to human RHOG (ras homolog family member G). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in spleen adult (RPKM 80.5), thymus adult (RPKM 76.7) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    7 E2; 7 54.71 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (101888330..101899325, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (102239123..102250118, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19704 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 10 Neighboring gene ADP-ribosyltransferase 1 Neighboring gene nucleoporin 98 Neighboring gene STARR-seq mESC enhancer starr_19705 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:109358847-109359078 Neighboring gene post-GPI attachment to proteins 2 Neighboring gene STARR-positive B cell enhancer ABC_E3738 Neighboring gene stromal interaction molecule 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:109486578-109486731 Neighboring gene STARR-positive B cell enhancer mm9_chr7:109495952-109496253 Neighboring gene methyltransferase like 6 pseudogene Neighboring gene STARR-seq mESC enhancer starr_19708 Neighboring gene STARR-positive B cell enhancer ABC_E9112 Neighboring gene STARR-seq mESC enhancer starr_19712 Neighboring gene ribonucleotide reductase M1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Rac protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within Rac protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within Rho protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in activation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cortical cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in establishment or maintenance of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cell shape IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of ruffle assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cell projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    rho-related GTP-binding protein RhoG
    Names
    aplysia ras-related homolog G (RhoG)
    ras homolog G (RhoG)
    ras homolog gene family, member G
    sid 10750

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019566.3NP_062512.1  rho-related GTP-binding protein RhoG

      See identical proteins and their annotated locations for NP_062512.1

      Status: VALIDATED

      Source sequence(s)
      AK143623, BQ942269
      Consensus CDS
      CCDS21529.1
      UniProtKB/Swiss-Prot
      P84096
      UniProtKB/TrEMBL
      Q3UDZ1
      Related
      ENSMUSP00000095832.5, ENSMUST00000098230.11
      Conserved Domains (1) summary
      cd01875
      Location:1191
      RhoG; Ras homolog family, member G (RhoG) of small guanosine triphosphatases (GTPases)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      101888330..101899325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)