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    Garin3 golgi associated RAB2 interactor 3 [ Mus musculus (house mouse) ]

    Gene ID: 432552, updated on 12-May-2024

    Summary

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    Official Symbol
    Garin3provided by MGI
    Official Full Name
    golgi associated RAB2 interactor 3provided by MGI
    Primary source
    MGI:MGI:3650836
    See related
    Ensembl:ENSMUSG00000020401 AllianceGenome:MGI:3650836
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam71b; Gari-l3
    Summary
    Predicted to be located in nucleus. Orthologous to human FAM71B (family with sequence similarity 71 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 78.7) See more
    Orthologs
    human all
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    Genomic context

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    See Garin3 in Genome Data Viewer
    Location:
    11 B1.1; 11 27.83 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (46295555..46298812)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (46404728..46407985)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene cytoplasmic FMR1 interacting protein 2 Neighboring gene high mobility group box 1 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:46124833-46125038 Neighboring gene STARR-positive B cell enhancer ABC_E8394 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:46140340-46140549 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:46157730-46157921 Neighboring gene IL2 inducible T cell kinase Neighboring gene predicted gene 12167 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:46202936-46203219 Neighboring gene STARR-positive B cell enhancer ABC_E3943 Neighboring gene STARR-seq mESC enhancer starr_29325 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:46234578-46234761 Neighboring gene STARR-seq mESC enhancer starr_29326 Neighboring gene STARR-positive B cell enhancer ABC_E1415 Neighboring gene predicted gene 12168 Neighboring gene mediator complex subunit 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity. Fukuda M, et al. Mol Cell Proteomics, 2008 Jun. PMID 18256213
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Golgi-associated RAB2B interactor protein 3
    Names
    Golgi associated RAB2B interactor protein 3
    Golgi-associated Rab2B interactor-like 3
    family with sequence similarity 71, member B
    protein FAM71B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013783.2 → NP_001013805.1  Golgi-associated RAB2B interactor protein 3

      See identical proteins and their annotated locations for NP_001013805.1

      Status: VALIDATED

      Source sequence(s)
      AL662806, AV282256, BB615215
      Consensus CDS
      CCDS24576.1
      UniProtKB/Swiss-Prot
      Q5STT6
      UniProtKB/TrEMBL
      B7XG48, B9EKM7
      Related
      ENSMUSP00000055079.6, ENSMUST00000063166.6
      Conserved Domains (2) summary
      pfam12480
      Location:120 → 187
      DUF3699; Protein of unknown function (DUF3699)
      pfam12871
      Location:499 → 572
      PRP38_assoc; Pre-mRNA-splicing factor 38-associated hydrophilic C-term

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      46295555..46298812
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5STT6.3 GenPept UniProtKB/Swiss-Prot:Q5STT6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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