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    cant1b calcium activated nucleotidase 1b [ Danio rerio (zebrafish) ]

    Gene ID: 445201, updated on 27-Mar-2024

    Summary

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    Official Symbol
    cant1bprovided by ZNC
    Official Full Name
    calcium activated nucleotidase 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-114
    See related
    Ensembl:ENSDARG00000102977 AllianceGenome:ZFIN:ZDB-GENE-040801-114
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101021
    Summary
    Predicted to enable calcium ion binding activity and nucleoside-diphosphatase activity. Human ortholog(s) of this gene implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7. Orthologous to human CANT1 (calcium activated nucleotidase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See cant1b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (45126408..45138857, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (44712014..44724463, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene si:dkey-93h22.8 Neighboring gene O-GlcNAcase like Neighboring gene si:dkey-93h22.4 Neighboring gene arylformamidase Neighboring gene thymidine kinase 1, soluble

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates. Kassahn KS, et al. Genome Res, 2009 Aug. PMID 19439512, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleoside diphosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    calcium activated nucleotidase 1b; soluble calcium-activated nucleotidase 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003595.2 → NP_001003595.1  soluble calcium-activated nucleotidase 1b

      See identical proteins and their annotated locations for NP_001003595.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078222
      UniProtKB/TrEMBL
      Q6DC62
      Related
      ENSDARP00000136156.1, ENSDART00000166501.2
      Conserved Domains (1) summary
      pfam06079
      Location:112 → 399
      Apyrase; Apyrase

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      45126408..45138857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009306325.3 → XP_009304600.1  calcium activated nucleotidase 1b isoform X2

      UniProtKB/TrEMBL
      A0A0R4IJX6, A0A8M3BDX0
      Conserved Domains (1) summary
      pfam06079
      Location:112 → 399
      Apyrase; Apyrase

    2. XM_009306324.3 → XP_009304599.1  calcium activated nucleotidase 1b isoform X1

      UniProtKB/TrEMBL
      A0A8M3AXZ6
      Conserved Domains (1) summary
      pfam06079
      Location:141 → 428
      Apyrase; Apyrase
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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