mogat2 monoacylglycerol O-acyltransferase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mogat2provided by ZNC
Official Full Name: monoacylglycerol O-acyltransferase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-186
See related: Ensembl:ENSDARG00000019228 AllianceGenome:ZFIN:ZDB-GENE-041010-186
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb94h05; zgc:101667
Summary: Predicted to enable 2-acylglycerol O-acyltransferase activity. Acts upstream of or within response to yeast. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in intestinal bulb and yolk syncytial layer. Orthologous to several human genes including MOGAT2 (monoacylglycerol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (32534814..32610776, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (32590954..32666916, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj53h01.x1 (e-PCR)
- UniSTS:188674

fb94h05.x1 (e-PCR)
- UniSTS:191850

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables 2-acylglycerol O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 2-acylglycerol O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables 2-methylhexanoyl-CoA C-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables diacylglycerol O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables keto acid formate lyase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in diacylglycerol biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within response to yeast	IDA Inferred from Direct Assay more info	PubMed
involved_in triglyceride biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 2-acylglycerol O-acyltransferase 2

Names: MGAT2

NP_001006083.2

EC 2.3.1.22

NP_001313629.1

EC 2.3.1.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006083.2 → NP_001006083.2 2-acylglycerol O-acyltransferase 2 isoform 2

Status: VALIDATED

Source sequence(s)

CR293504, CT573240

UniProtKB/TrEMBL

A0A8M1N2V8, F1QSW7

Related

ENSDARP00000009175.8, ENSDART00000017436.9
NM_001326700.1 → NP_001313629.1 2-acylglycerol O-acyltransferase 2 isoform 1

Status: VALIDATED

Source sequence(s)

CR293504

UniProtKB/TrEMBL

A0A8M1P3L0, F1R0E7

Related

ENSDARP00000104851.1, ENSDART00000128888.3

Conserved Domains (1) summary

pfam03982
Location:73 → 368

DAGAT; Diacylglycerol acyltransferase