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    Hirip3 HIRA interacting protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 233876, updated on 9-May-2024

    Summary

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    Official Symbol
    Hirip3provided by MGI
    Official Full Name
    HIRA interacting protein 3provided by MGI
    Primary source
    MGI:MGI:2142364
    See related
    Ensembl:ENSMUSG00000042606 AllianceGenome:MGI:2142364
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B130036O03
    Summary
    Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Is expressed in central nervous system; genitourinary system; and intestine. Orthologous to human HIRIP3 (HIRA interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 42.6), liver E14 (RPKM 25.5) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Hirip3 in Genome Data Viewer
    Location:
    7 F3; 7 69.25 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126461155..126464549)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126861929..126865377)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930451I11 gene Neighboring gene double C2, alpha Neighboring gene INO80 complex subunit E Neighboring gene STARR-positive B cell enhancer ABC_E8843 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134005673-134005856 Neighboring gene TAO kinase 2 Neighboring gene STARR-positive B cell enhancer ABC_E2849 Neighboring gene transmembrane protein 219 Neighboring gene predicted gene, 23445

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3. Magnaghi P, et al. Nat Genet, 1998 Sep. PMID 9731536
    2. Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator. Maier VK, et al. Mol Cell Proteomics, 2015 Jun. PMID 25680957, Free PMC Article
    3. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    HIRA-interacting protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001421792.1 → NP_001408721.1  HIRA-interacting protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124505

    2. NM_001421795.1 → NP_001408724.1  HIRA-interacting protein 3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC124505

    3. NM_001421797.1 → NP_001408726.1  HIRA-interacting protein 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124505

    4. NM_001421799.1 → NP_001408728.1  HIRA-interacting protein 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124505

    5. NM_001421801.1 → NP_001408730.1  HIRA-interacting protein 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC124505

    6. NM_172746.4 → NP_766334.1  HIRA-interacting protein 3 isoform 1

      See identical proteins and their annotated locations for NP_766334.1

      Status: VALIDATED

      Source sequence(s)
      AC124505
      Consensus CDS
      CCDS21849.1
      UniProtKB/Swiss-Prot
      Q3TSF3, Q8BLH7
      Related
      ENSMUSP00000035535.4, ENSMUST00000037248.10
      Conserved Domains (1) summary
      smart01082
      Location:529 → 565
      CHZ; Histone chaperone domain CHZ

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      126461155..126464549
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001785541.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BLH7.1 GenPept UniProtKB/Swiss-Prot:Q8BLH7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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