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    Tmem151a transmembrane protein 151A [ Mus musculus (house mouse) ]

    Gene ID: 381199, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Tmem151aprovided by MGI
    Official Full Name
    transmembrane protein 151Aprovided by MGI
    Primary source
    MGI:MGI:2147713
    See related
    Ensembl:ENSMUSG00000061451 AllianceGenome:MGI:2147713
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm961; Gm30627; Tmem151
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in diencephalon mantle layer; hypothalamus mantle layer; and thalamus mantle layer. Orthologous to human TMEM151A (transmembrane protein 151A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in stomach adult (RPKM 43.1), cortex adult (RPKM 36.1) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem151a in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5120859..5135519, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5079333..5085491, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 1 Neighboring gene STARR-positive B cell enhancer ABC_E1968 Neighboring gene uncharacterized LOC132660285 Neighboring gene STARR-positive B cell enhancer ABC_E7627 Neighboring gene CD248 antigen, endosialin Neighboring gene Yip1 interacting factor homolog A (S. cerevisiae) Neighboring gene cornichon family AMPA receptor auxiliary protein 2 Neighboring gene RAB1B, member RAS oncogene family Neighboring gene STARR-positive B cell enhancer ABC_E1969

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. TMEM151A variants cause paroxysmal kinesigenic dyskinesia. Li HF, et al. Cell Discov, 2021 Sep 13. PMID 34518509, Free PMC Article
    2. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 151A
    Names
    transmembrane protein 151

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001885.2 → NP_001001885.1  transmembrane protein 151A

      See identical proteins and their annotated locations for NP_001001885.1

      Status: VALIDATED

      Source sequence(s)
      AC124502, BC072634
      Consensus CDS
      CCDS29449.1
      UniProtKB/Swiss-Prot
      Q6GQT5
      Related
      ENSMUSP00000076321.8, ENSMUST00000077066.8
      Conserved Domains (1) summary
      pfam14857
      Location:26 → 423
      TMEM151; TMEM151 family

    RNA

    1. NR_166780.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502

    2. NR_166781.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502

    3. NR_166782.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502

    4. NR_166783.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502

    5. NR_166784.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502
      Related
      ENSMUST00000143677.2

    6. NR_166785.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502

    7. NR_166786.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124502

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5120859..5135519 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6GQT5.1 GenPept UniProtKB/Swiss-Prot:Q6GQT5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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