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    SRG3 senescence-related gene 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821175, updated on 15-Oct-2023

    Summary

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    Gene symbol
    SRG3
    Gene description
    senescence-related gene 3
    Primary source
    Araport:AT3G02040
    Locus tag
    AT3G02040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGDPD1; F1C9.18; F1C9_18; GDPD1; Glycerophosphodiester phosphodiesterase 1; senescence-related gene 3
    Summary
    Encodes a member of the glycerophosphodiester phosphodiesterase (GDPD) family. Has glycerophosphodiester phosphodiesterase activity. Functions in maintaining cellular phosphate homeostasis under phosphate starvation.
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    Genomic context

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    See SRG3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (348167..350010, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ACT domain repeat 6 Neighboring gene Thioredoxin superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene aspartate kinase 3 Neighboring gene transferase Neighboring gene K+ uptake transporter 3 Neighboring gene DEAD/DEAH box helicase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the Arabidopsis glycerophosphodiester phosphodiesterase (GDPD) family reveals a role of the plastid-localized AtGDPD1 in maintaining cellular phosphate homeostasis under phosphate starvation. Cheng Y, et al. Plant J, 2011 Jun. PMID 21323773
    2. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_111070.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycerophosphodiester phosphodiesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within intracellular phosphate ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    senescence-related gene 3
    NP_566159.1
    • senescence-related gene 3 (SRG3); FUNCTIONS IN: phosphoric diester hydrolase activity, glycerophosphodiester phosphodiesterase activity; INVOLVED IN: glycerol metabolic process, lipid metabolic process; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: PLC-like phosphodiesterase, TIM beta/alpha-barrel domain (InterPro:IPR017946), Glycerophosphoryl diester phosphodiesterase (InterPro:IPR004129); BEST Arabidopsis thaliana protein match is: PLC-like phosphodiesterases superfamily protein (TAIR:AT5G41080.1); Has 1727 Blast hits to 1696 proteins in 532 species: Archae - 28; Bacteria - 1003; Metazoa - 245; Fungi - 173; Plants - 101; Viruses - 2; Other Eukaryotes - 175 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      348167..350010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111070.4 → NP_566159.1  senescence-related gene 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566159.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84WI7, Q9SGA2
      UniProtKB/TrEMBL
      A0A178VC35, A0A654F3B3
      Conserved Domains (1) summary
      cl14615
      Location:35 → 316
      PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SGA2.1

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