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    2010315B03Rik RIKEN cDNA 2010315B03 gene [ Mus musculus (house mouse) ]

    Gene ID: 630836, updated on 8-Feb-2024

    Summary

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    Official Symbol
    2010315B03Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 2010315B03 geneprovided by MGI
    Primary source
    MGI:MGI:1919321
    See related
    Ensembl:ENSMUSG00000074829 AllianceGenome:MGI:1919321
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 6.2), frontal lobe adult (RPKM 3.2) and 24 other tissues See more
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    Genomic context

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    See 2010315B03Rik in Genome Data Viewer
    Location:
    9; 9 F4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (124054432..124075349, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (124291802..124312719, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5117 Neighboring gene C-C motif chemokine receptor 5 Neighboring gene predicted gene, 39469 Neighboring gene NLR family, pyrin domain containing 4G Neighboring gene predicted gene, 20783

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC630836

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243117.1 → NP_001230046.1  uncharacterized protein LOC630836 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AA178344, AK008571, CAAA01180111, CK618160
      Conserved Domains (5) summary
      smart00349
      Location:29 → 70
      KRAB; krueppel associated box
      COG5048
      Location:98 → 454
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:186 → 206
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:29 → 68
      KRAB; KRAB box
      pfam13465
      Location:226 → 251
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001243118.1 → NP_001230047.1  uncharacterized protein LOC630836 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon and includes an alternate in-frame exon in the coding region, compared to variant 1. The resulting protein (isoform 2) is shorter, compared to isoform 1.
      Source sequence(s)
      AA178344, AK008571, CAAA01180111, CN530830
      Conserved Domains (5) summary
      smart00349
      Location:25 → 66
      KRAB; krueppel associated box
      COG5048
      Location:94 → 450
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:182 → 202
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:25 → 64
      KRAB; KRAB box
      pfam13465
      Location:222 → 247
      zf-H2C2_2; Zinc-finger double domain

    3. NM_001243119.1 → NP_001230048.1  uncharacterized protein LOC630836 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting protein (isoform 3) is shorter, compared to isoform 1.
      Source sequence(s)
      AA178344, AK008571, BC029716, CAAA01180111
      Consensus CDS
      CCDS81096.1
      UniProtKB/TrEMBL
      J3QK55
      Related
      ENSMUSP00000137258.3, ENSMUST00000177714.8
      Conserved Domains (5) summary
      smart00349
      Location:4 → 45
      KRAB; krueppel associated box
      COG5048
      Location:73 → 429
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:161 → 181
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 43
      KRAB; KRAB box
      pfam13465
      Location:201 → 226
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      124054432..124075349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249866.3 → XP_011248168.1  uncharacterized protein LOC630836 isoform X1

      See identical proteins and their annotated locations for XP_011248168.1

      Conserved Domains (3) summary
      COG5048
      Location:119 → 475
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:207 → 227
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:50 → 90
      KRAB; KRAB box

    2. XM_036155167.1 → XP_036011060.1  uncharacterized protein LOC630836 isoform X2

      Conserved Domains (1) summary
      pfam01352
      Location:29 → 69
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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