Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sult2a2provided by MGI
Official Full Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2provided by MGI
Primary source: MGI:MGI:107550
See related: Ensembl:ENSMUSG00000070811 AllianceGenome:MGI:107550
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: ST; Sth2; ST2A2; mSTa2; C730007P19Rik
Summary: Predicted to enable 3'-phosphoadenosine 5'-phosphosulfate binding activity and sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; ethanol catabolic process; and thyroid hormone metabolic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward liver adult (RPKM 35.7) See more
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Genomic context

Location:: 7 A1; 7 8.0 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (13467431..13513562)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (13733506..13779637)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:495478

NoName (e-PCR)
- UniSTS:488345

NoName (e-PCR)
- UniSTS:487672

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables 3'-phosphoadenosine 5'-phosphosulfate binding	ISO Inferred from Sequence Orthology more info
enables alcohol sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables bile-salt sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables steroid sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 3'-phosphoadenosine 5'-phosphosulfate metabolic process	ISO Inferred from Sequence Orthology more info
involved_in cholesterol metabolic process	ISO Inferred from Sequence Orthology more info
involved_in ethanol catabolic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in steroid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in sulfation	IBA Inferred from Biological aspect of Ancestor more info
involved_in sulfation	ISO Inferred from Sequence Orthology more info
involved_in thyroid hormone metabolic process	ISO Inferred from Sequence Orthology more info
involved_in xenobiotic metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: sulfotransferase 2A2

Names: bile salt sulfotransferase 2; hydroxysteroid sulfotransferase; sulfotransferase, hydroxysteroid preferring 2

NP_033312.2

EC 2.8.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.