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    ap1s2 adaptor related protein complex 1 subunit sigma 2 [ Danio rerio (zebrafish) ]

    Gene ID: 327237, updated on 25-Apr-2024

    Summary

    Official Symbol
    ap1s2provided by ZNC
    Official Full Name
    adaptor related protein complex 1 subunit sigma 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5448
    See related
    Ensembl:ENSDARG00000058504 AllianceGenome:ZFIN:ZDB-GENE-030131-5448
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:65824; zgc:77925; wu:fb94g06; wu:fd19a08
    Summary
    Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be part of membrane coat. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 5. Orthologous to human AP1S2 (adaptor related protein complex 1 subunit sigma 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    See ap1s2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (12720014..12728349)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (12662355..12670690)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RBBP6-like Neighboring gene E3 ubiquitin-protein ligase RBBP6-like Neighboring gene zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 Neighboring gene retinoblastoma binding protein 4, like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables clathrin adaptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of AP-1 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in clathrin-coated pit IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    AP-1 complex subunit sigma-2
    Names
    adaptor-related protein complex 1, sigma 2 subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205558.1NP_991121.1  AP-1 complex subunit sigma-2

      See identical proteins and their annotated locations for NP_991121.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065471
      UniProtKB/TrEMBL
      A0A0G2KXM8, A0A8N7XJN0, F6PAJ6, Q6P0R9
      Related
      ENSDARP00000054836.6, ENSDART00000054837.8
      Conserved Domains (1) summary
      pfam01217
      Location:1141
      Clat_adaptor_s; Clathrin adaptor complex small chain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      12720014..12728349
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_3

    Genomic

    1. NW_018395384.1 Reference GRCz11 ALT_DRER_TU_3

      Range
      437991..446326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)