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    Grcc10 gene rich cluster, C10 gene [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100362005, updated on 13-Apr-2024

    Summary

    Symbol
    Grcc10provided by RGD
    Full Name
    gene rich cluster, C10 geneprovided by RGD
    Primary source
    RGD:2318975
    See related
    AllianceGenome:RGD:2318975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in several processes, including animal organ development; psychomotor behavior; and regulation of skeletal muscle contraction. Predicted to be located in cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in Temtamy syndrome. Orthologous to human C12orf57 (chromosome 12 open reading frame 57). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 554.5), Kidney (RPKM 509.7) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Grcc10 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (159237562..159239223, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (157551276..157552924, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (157264383..157266042, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene microRNA 3575 Neighboring gene microRNA 200c Neighboring gene protein tyrosine phosphatase, non-receptor type 6 Neighboring gene U7 small nuclear RNA Neighboring gene atrophin 1 Neighboring gene uncharacterized LOC120102384 Neighboring gene enolase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in camera-type eye morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cognition ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in corpus callosum morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in post-embryonic development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in post-embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in psychomotor behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of skeletal muscle contraction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in third ventricle development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein C10
    Names
    C10 protein
    protein C10-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001198725.1NP_001185654.1  protein C10

      See identical proteins and their annotated locations for NP_001185654.1

      Status: VALIDATED

      Source sequence(s)
      FM049692, FM062242, JAXUCZ010000004
      UniProtKB/TrEMBL
      A6ILJ6, A6ILJ7
      Conserved Domains (1) summary
      pfam14974
      Location:11113
      P_C10; Protein C10

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      159237562..159239223 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237325.5XP_006237387.1  protein C10 isoform X1

      See identical proteins and their annotated locations for XP_006237387.1

      Conserved Domains (1) summary
      pfam14974
      Location:1176
      DUF4511; Domain of unknown function (DUF4511)