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    Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 [ Mus musculus (house mouse) ]

    Gene ID: 72094, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Ugt2a3provided by MGI
    Official Full Name
    UDP glucuronosyltransferase 2 family, polypeptide A3provided by MGI
    Primary source
    MGI:MGI:1919344
    See related
    Ensembl:ENSMUSG00000035780 AllianceGenome:MGI:1919344
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010321J07Rik
    Summary
    Predicted to enable glucuronosyltransferase activity. Predicted to be involved in cellular glucuronidation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in nervous system; nose; and olfactory epithelium. Orthologous to human UGT2A3 (UDP glucuronosyltransferase family 2 member A3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in liver adult (RPKM 48.1), duodenum adult (RPKM 5.4) and 2 other tissues See more
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    Genomic context

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    See Ugt2a3 in Genome Data Viewer
    Location:
    5 E1; 5 43.56 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (87472694..87485054, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (87324972..87337195, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B37 Neighboring gene STARR-seq mESC enhancer starr_13557 Neighboring gene predicted gene 7646 Neighboring gene UDP-glucuronosyltransferase 2A1-like Neighboring gene isopentenyl-diphosphate delta isomerase, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Chen S, et al. Proc Natl Acad Sci U S A, 2017 Feb 21. PMID 28167773, Free PMC Article
    2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucuronosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular glucuronidation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucuronosyltransferase 2A3
    Names
    UDPGT 2A3
    NP_082370.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028094.4 → NP_082370.2  UDP-glucuronosyltransferase 2A3 precursor

      See identical proteins and their annotated locations for NP_082370.2

      Status: VALIDATED

      Source sequence(s)
      AC101835
      Consensus CDS
      CCDS19387.1
      UniProtKB/Swiss-Prot
      Q8BWQ1, Q8R129, Q9D811
      Related
      ENSMUSP00000031195.3, ENSMUST00000031195.3
      Conserved Domains (2) summary
      PHA03392
      Location:268 → 507
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:25 → 526
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      87472694..87485054 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BWQ1.1 GenPept UniProtKB/Swiss-Prot:Q8BWQ1

    Gene LinkOut

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