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    ATP5F1A ATP synthase F1 subunit alpha [ Sus scrofa (pig) ]

    Gene ID: 100157880, updated on 8-Mar-2024

    Summary

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    Official Symbol
    ATP5F1Aprovided by VGNC
    Official Full Name
    ATP synthase F1 subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:109475
    See related
    Ensembl:ENSSSCG00000004499
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    ATP5A1; ATP5A2
    Expression
    Ubiquitous expression in heart (RPKM 1037.9), psoas major muscle (RPKM 741.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See ATP5F1A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (95738789..95750835, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (105944306..105955798)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene ectopic P-granules 5 autophagy tethering factor Neighboring gene proline-serine-threonine phosphatase interacting protein 2 Neighboring gene acyl-CoA-binding protein pseudogene Neighboring gene HAUS augmin like complex subunit 1 Neighboring gene arkadia (RNF111) N-terminal like PKA signaling regulator 2N

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Localization on the mitochondrial F1 ATPase alpha subunit of an epitope masked in the membrane-bound enzyme using a monoclonal antibody and synthetic peptides. Moradi-Améli M, et al. Eur J Biochem, 1991 Aug 1. PMID 1714390
    2. Evaluation and characterization of a porcine small intestine cDNA library: analysis of 839 clones. Wintero AK, et al. Mamm Genome, 1996 Jul. PMID 8672129
    3. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables proton-transporting ATP synthase activity, rotational mechanism IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proton motive force-driven ATP synthesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial proton-transporting ATP synthase, catalytic core IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of proton-transporting ATP synthase complex, catalytic core F(1) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP synthase subunit alpha, mitochondrial
    Names
    ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
    cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001185142.1 → NP_001172071.1  ATP synthase subunit alpha, mitochondrial

      See identical proteins and their annotated locations for NP_001172071.1

      Status: PROVISIONAL

      Source sequence(s)
      EU650784
      UniProtKB/Swiss-Prot
      B2ZF46, P80021, Q29596
      UniProtKB/TrEMBL
      A0A4X1USY4, A0A8D0ZJG9
      Related
      ENSSSCP00000037224.1, ENSSSCT00000056853.2
      Conserved Domains (4) summary
      PRK09281
      Location:49 → 553
      PRK09281; F0F1 ATP synthase subunit alpha; Validated
      cd01132
      Location:137 → 418
      F1_ATPase_alpha; F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to ...
      pfam00306
      Location:427 → 521
      ATP-synt_ab_C; ATP synthase alpha/beta chain, C terminal domain
      pfam02874
      Location:69 → 135
      ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      95738789..95750835 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P80021.2 GenPept UniProtKB/Swiss-Prot:P80021

    Gene LinkOut

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