Zcwpw2 zinc finger, CW type with PWWP domain 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zcwpw2provided by MGI
Official Full Name: zinc finger, CW type with PWWP domain 2provided by MGI
Primary source: MGI:MGI:1921888
See related: Ensembl:ENSMUSG00000032443 AllianceGenome:MGI:1921888
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4930430K04Rik
Summary: Predicted to enable methylated histone binding activity. Predicted to be active in nucleus. Orthologous to human ZCWPW2 (zinc finger CW-type and PWWP domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 9 F3; 9 69.83 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (117752903..117869927, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (117923835..118040859, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

G65766 (e-PCR)
- UniSTS:225900

NoName (e-PCR)
- UniSTS:490610

RH94076 (e-PCR)
- UniSTS:87970

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables methylated histone binding	IBA Inferred from Biological aspect of Ancestor more info
enables methylated histone binding	ISO Inferred from Sequence Orthology more info
enables molecular_function	ND No biological Data available more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger CW-type PWWP domain protein 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001378466.1 → NP_001365395.1 zinc finger CW-type PWWP domain protein 2 homolog

Status: VALIDATED

Source sequence(s)

AC157475, AC165253

UniProtKB/Swiss-Prot

A0A5F8MP94, Q08EN7

Related

ENSMUSP00000158867.2, ENSMUST00000238919.2

Conserved Domains (2) summary

pfam07496
Location:14 → 62

zf-CW; CW-type Zinc Finger

cl02554
Location:82 → 155

PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...