cd9b CD9 molecule b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cd9bprovided by ZNC
Official Full Name: CD9 molecule bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2768
See related: Ensembl:ENSDARG00000016691 AllianceGenome:ZFIN:ZDB-GENE-040426-2768
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cd9l; fb82b11; zgc:56512; wu:fb82b11
Summary: Acts upstream of or within posterior lateral line development. Predicted to be located in extracellular region and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including EVL; epidermis; periderm; pronephric duct; and sensory system. Human ortholog(s) of this gene implicated in prostate adenocarcinoma. Orthologous to human CD9 (CD9 molecule). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 4

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (4234994..4261623, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (4226081..4252710, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tetraspanin Cd9b plays a role in fertility in zebrafish.
Title: Tetraspanin Cd9b plays a role in fertility in zebrafish.
Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration.
Title: Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration.

Submit: New GeneRIF Correction

General gene information

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Markers

fb13e10.x1 (e-PCR)
- UniSTS:202899

AW202864 (e-PCR)
- UniSTS:205723

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within posterior lateral line development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within single fertilization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CD9 antigen; CD9 molecule b

Names: CD9 antigen, b; CD9 antigen, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213428.2 → NP_998593.1 CD9 molecule b

See identical proteins and their annotated locations for NP_998593.1

Status: PROVISIONAL

Source sequence(s)

BC049036

UniProtKB/TrEMBL

Q7ZUH9

Related

ENSDARP00000094096.3, ENSDART00000103319.5

Conserved Domains (2) summary

cd03152
Location:109 → 192

CD9_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD9 family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans ...

pfam00335
Location:9 → 220

Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007115.7 Reference GRCz11 Primary Assembly

Range

4234994..4261623 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005164484.2 → XP_005164541.1 CD9 antigen isoform X1

UniProtKB/TrEMBL

A0A8M2BBY1, Q1L9G6

Related

ENSDARP00000026201.6, ENSDART00000026559.8

Conserved Domains (2) summary

cd03152
Location:113 → 196

CD9_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD9 family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans ...

pfam00335
Location:13 → 224

Tetraspannin; Tetraspanin family