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    ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma [ Danio rerio (zebrafish) ]

    Gene ID: 393100, updated on 27-Mar-2024

    Summary

    Official Symbol
    ppp2r3cprovided by ZNC
    Official Full Name
    protein phosphatase 2, regulatory subunit B'', gammaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-715
    See related
    Ensembl:ENSDARG00000043972 AllianceGenome:ZFIN:ZDB-GENE-040426-715
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55473
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in cytoskeleton organization; lymphocyte homeostasis; and positive regulation of B cell differentiation. Predicted to act upstream of or within regulation of dephosphorylation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Orthologous to human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See ppp2r3c in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (13007307..13019638)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (12853241..12865572)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene proteasome 20S subunit alpha 6a Neighboring gene protein only RNase P catalytic subunit Neighboring gene family with sequence similarity 177 member A1 Neighboring gene F-box protein 33 Neighboring gene MIA SH3 domain ER export factor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC55473

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in B cell homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in T cell homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cortical cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of B cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200131.1NP_956425.1  serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

      See identical proteins and their annotated locations for NP_956425.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044178
      UniProtKB/Swiss-Prot
      Q803V3
      UniProtKB/TrEMBL
      B2GT25
      Related
      ENSDARP00000064553.3, ENSDART00000064554.4

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      13007307..13019638
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)