U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Mfsd14b major facilitator superfamily domain containing 14B [ Mus musculus (house mouse) ]

    Gene ID: 66631, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Mfsd14bprovided by MGI
    Official Full Name
    major facilitator superfamily domain containing 14Bprovided by MGI
    Primary source
    MGI:MGI:1913881
    See related
    Ensembl:ENSMUSG00000038212 AllianceGenome:MGI:1913881
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hiatl1; 5730414C17Rik
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human MFSD14B (major facilitator superfamily domain containing 14B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 14.5), placenta adult (RPKM 12.6) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Mfsd14b in Genome Data Viewer
    Location:
    13 B3; 13 34.21 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (65212843..65260813, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (65065030..65112999, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 31 subfamily D, member 1C Neighboring gene serine protease 47 Neighboring gene predicted gene 3785 Neighboring gene olfactory receptor family 14 subfamily P member 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    2. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Murn J, et al. Genes Dev, 2015 Mar 1. PMID 25737280, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    hippocampus abundant transcript-like protein 1
    Names
    hippocampus abundant transcript-like 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083901.2 → NP_001077370.1  hippocampus abundant transcript-like protein 1

      See identical proteins and their annotated locations for NP_001077370.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1.
      Source sequence(s)
      AC154713
      Consensus CDS
      CCDS26603.2
      UniProtKB/Swiss-Prot
      G3UVV2, Q8CIA9, Q8VCW0
      Related
      ENSMUSP00000062566.9, ENSMUST00000054730.10
      Conserved Domains (1) summary
      cd17387
      Location:47 → 452
      MFS_MFSD14; Major facilitator superfamily domain-containing 14A and 14B

    2. NM_133680.4 → NP_598441.3  hippocampus abundant transcript-like protein 1

      See identical proteins and their annotated locations for NP_598441.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC154713
      Consensus CDS
      CCDS26603.2
      UniProtKB/Swiss-Prot
      G3UVV2, Q8CIA9, Q8VCW0
      Related
      ENSMUSP00000118180.2, ENSMUST00000155487.8
      Conserved Domains (1) summary
      cd17387
      Location:47 → 452
      MFS_MFSD14; Major facilitator superfamily domain-containing 14A and 14B

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      65212843..65260813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244550.4 → XP_011242852.1  hippocampus abundant transcript-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242852.1

      UniProtKB/Swiss-Prot
      G3UVV2, Q8CIA9, Q8VCW0
      Conserved Domains (1) summary
      cd17387
      Location:47 → 452
      MFS_MFSD14; Major facilitator superfamily domain-containing 14A and 14B
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CIA9.3 GenPept UniProtKB/Swiss-Prot:Q8CIA9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous