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    Sema6c sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C [ Mus musculus (house mouse) ]

    Gene ID: 20360, updated on 12-May-2024

    Summary

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    Official Symbol
    Sema6cprovided by MGI
    Official Full Name
    sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Cprovided by MGI
    Primary source
    MGI:MGI:1338032
    See related
    Ensembl:ENSMUSG00000038777 AllianceGenome:MGI:1338032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Semay; mKIAA1869
    Summary
    Enables semaphorin receptor binding activity. Predicted to be involved in several processes, including generation of neurons; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be located in cell surface and cytoplasm. Predicted to be active in extracellular space. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Orthologous to human SEMA6C (semaphorin 6C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in whole brain E14.5 (RPKM 28.2), CNS E14 (RPKM 23.1) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sema6c in Genome Data Viewer
    Location:
    3 F2.1; 3 40.74 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95067731..95081361)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95160420..95174050)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:94945477-94945712 Neighboring gene LysM, putative peptidoglycan-binding, domain containing 1 Neighboring gene tumor necrosis factor, alpha-induced protein 8-like 2 Neighboring gene predicted gene 9169 Neighboring gene STARR-seq mESC enhancer starr_08369 Neighboring gene GA repeat binding protein, beta 2 Neighboring gene STARR-seq mESC enhancer starr_08372 Neighboring gene predicted gene, 16740 Neighboring gene myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 Neighboring gene CDC42 small effector 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Suppression of SEMA6C promotes preantral follicles atresia with decreased cell junctions in mice ovaries. Yan W, et al. J Cell Physiol, 2019 Apr. PMID 30256425
    2. Low expression of SEMA6C accelerates the primordial follicle activation in the neonatal mouse ovary. Zhou S, et al. J Cell Mol Med, 2018 Jan. PMID 28881413, Free PMC Article
    3. Semaphorin 6C expression in innervated and denervated skeletal muscle. Svensson A, et al. J Mol Histol, 2008 Feb. PMID 17605078
    4. Semaphorin 6C leads to GSK-3-dependent growth cone collapse and redistributes after entorhino-hippocampal axotomy. Burgaya F, et al. Mol Cell Neurosci, 2006 Nov. PMID 17029982
    5. Sema6B, Sema6C, and Sema6D expression and function during mammalian retinal development. Matsuoka RL, et al. PLoS One, 2013. PMID 23646199, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Sema6c was involved in follicle development, and the suppression of SEMA6C led to cell junction defection by activating the PI3K/AKT pathway.
      Title: Suppression of SEMA6C promotes preantral follicles atresia with decreased cell junctions in mice ovaries.
    2. down-regulation of SEMA6C led to massive primordial follicle activation.
      Title: Low expression of SEMA6C accelerates the primordial follicle activation in the neonatal mouse ovary.
    3. Class 6 transmembrane semaphorins are unlikely to serve as major PlexA receptor ligands for the assembly of murine retinal circuit laminar organization.
      Title: Sema6B, Sema6C, and Sema6D expression and function during mammalian retinal development.
    4. The expression of Semaphorin 6C mRNA and immunoreactivity has been compared in innervated and denervated mouse hind-limb and hemidiaphragm muscles.
      Title: Semaphorin 6C expression in innervated and denervated skeletal muscle.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Gene trapped (1) 
    • Targeted (2)  1 citation

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chemorepellent activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables semaphorin receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables semaphorin receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in axon guidance ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neural crest cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in semaphorin-plexin signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    semaphorin-6C
    Names
    Sema Y
    m-Sema Y
    semaphorin-Y

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001272024.2 → NP_001258953.1  semaphorin-6C isoform 1 precursor

      See identical proteins and their annotated locations for NP_001258953.1

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      Consensus CDS
      CCDS71289.1
      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Related
      ENSMUSP00000088333.2, ENSMUST00000090823.8
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    2. NM_001428690.1 → NP_001415619.1  semaphorin-6C isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      UniProtKB/TrEMBL
      E9Q613

    3. NM_001428691.1 → NP_001415620.1  semaphorin-6C isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      UniProtKB/TrEMBL
      E9Q613

    4. NM_001428692.1 → NP_001415621.1  semaphorin-6C isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      UniProtKB/TrEMBL
      E9Q613

    5. NM_001428693.1 → NP_001415622.1  semaphorin-6C isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      UniProtKB/Swiss-Prot
      Q9WTM3

    6. NM_001428694.1 → NP_001415623.1  semaphorin-6C isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      UniProtKB/Swiss-Prot
      Q9WTM3

    7. NM_001428695.1 → NP_001415624.1  semaphorin-6C isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      UniProtKB/Swiss-Prot
      Q9WTM3

    8. NM_001428696.1 → NP_001415625.1  semaphorin-6C isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    9. NM_011351.3 → NP_035481.1  semaphorin-6C isoform 2 precursor

      See identical proteins and their annotated locations for NP_035481.1

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      Consensus CDS
      CCDS17604.1
      UniProtKB/Swiss-Prot
      Q9WTM3
      UniProtKB/TrEMBL
      Q91Y36
      Related
      ENSMUSP00000144039.2, ENSMUST00000202315.3
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:686 → 929
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    RNA

    1. NR_073549.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      Related
      ENSMUST00000204709.3

    2. NR_073550.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190
      Related
      ENSMUST00000142449.9

    3. NR_073551.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    4. NR_190459.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    5. NR_190460.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    6. NR_190461.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    7. NR_190462.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    8. NR_190463.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    9. NR_190464.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    10. NR_190465.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    11. NR_190466.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    12. NR_190467.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    13. NR_190468.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131769, AC140190

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      95067731..95081361
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501205.1 → XP_006501268.1  semaphorin-6C isoform X2

      Related
      ENSMUSP00000088331.4, ENSMUST00000090821.10
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:686 → 929
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    2. XM_036162976.1 → XP_036018869.1  semaphorin-6C isoform X3

      UniProtKB/TrEMBL
      Q91Y36
      Conserved Domains (3) summary
      PHA03247
      Location:680 → 922
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:485 → 537
      PSI; Plexin repeat
      cl15693
      Location:54 → 484
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    3. XM_006501194.4 → XP_006501257.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501257.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    4. XM_030252487.1 → XP_030108347.1  semaphorin-6C isoform X2

      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:686 → 929
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    5. XM_006501192.5 → XP_006501255.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501255.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    6. XM_030252503.2 → XP_030108363.1  semaphorin-6C isoform X17

      Conserved Domains (3) summary
      smart00423
      Location:88 → 109
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:283 → 525
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 87
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    7. XM_006501193.4 → XP_006501256.1  semaphorin-6C isoform X1

      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    8. XM_030252486.1 → XP_030108346.1  semaphorin-6C isoform X2

      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:686 → 929
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    9. XM_006501201.5 → XP_006501264.1  semaphorin-6C isoform X1

      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    10. XM_006501195.4 → XP_006501258.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501258.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    11. XM_006501196.4 → XP_006501259.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501259.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    12. XM_036162977.1 → XP_036018870.1  semaphorin-6C isoform X5

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:656 → 898
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:461 → 482
      PSI; Plexin repeat
      cl15693
      Location:126 → 460
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    13. XM_006501207.4 → XP_006501270.1  semaphorin-6C isoform X6

      UniProtKB/TrEMBL
      Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:456 → 477
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:651 → 893
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:16 → 455
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    14. XM_006501197.4 → XP_006501260.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501260.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    15. XM_006501198.4 → XP_006501261.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501261.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    16. XM_006501202.4 → XP_006501265.1  semaphorin-6C isoform X1

      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    17. XM_006501204.4 → XP_006501267.1  semaphorin-6C isoform X1

      See identical proteins and their annotated locations for XP_006501267.1

      UniProtKB/TrEMBL
      E9Q613, Q91Y36
      Related
      ENSMUSP00000129081.3, ENSMUST00000168321.8
      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:714 → 956
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    18. XM_030252491.1 → XP_030108351.1  semaphorin-6C isoform X10

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:606 → 848
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    19. XM_030252489.2 → XP_030108349.1  semaphorin-6C isoform X2

      Conserved Domains (3) summary
      smart00423
      Location:519 → 540
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:686 → 929
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:54 → 518
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    20. XM_006501208.4 → XP_006501271.1  semaphorin-6C isoform X12

      See identical proteins and their annotated locations for XP_006501271.1

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      smart00423
      Location:372 → 393
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:567 → 809
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 371
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    21. XM_036162982.1 → XP_036018875.1  semaphorin-6C isoform X13

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:547 → 789
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:352 → 373
      PSI; Plexin repeat
      cl15693
      Location:17 → 351
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    22. XM_030252501.1 → XP_030108361.1  semaphorin-6C isoform X12

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      smart00423
      Location:372 → 393
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:567 → 809
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 371
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    23. XM_030252492.1 → XP_030108352.1  semaphorin-6C isoform X10

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:606 → 848
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    24. XM_030252495.1 → XP_030108355.1  semaphorin-6C isoform X11

      Conserved Domains (3) summary
      PHA03247
      Location:578 → 821
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    25. XM_030252490.1 → XP_030108350.1  semaphorin-6C isoform X8

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      smart00423
      Location:479 → 500
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:646 → 889
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:39 → 478
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    26. XM_030252505.1 → XP_030108365.1  semaphorin-6C isoform X18

      Conserved Domains (3) summary
      smart00423
      Location:88 → 109
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:213 → 453
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 87
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    27. XM_030252504.1 → XP_030108364.1  semaphorin-6C isoform X18

      Conserved Domains (3) summary
      smart00423
      Location:88 → 109
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:213 → 453
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 87
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    28. XM_036162978.1 → XP_036018871.1  semaphorin-6C isoform X7

      Conserved Domains (3) summary
      PHA03247
      Location:652 → 895
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:485 → 537
      PSI; Plexin repeat
      cl15693
      Location:54 → 484
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    29. XM_036162983.1 → XP_036018876.1  semaphorin-6C isoform X13

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:547 → 789
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:352 → 373
      PSI; Plexin repeat
      cl15693
      Location:17 → 351
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    30. XM_006501209.4 → XP_006501272.1  semaphorin-6C isoform X12

      See identical proteins and their annotated locations for XP_006501272.1

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      smart00423
      Location:372 → 393
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:567 → 809
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 371
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    31. XM_030252506.1 → XP_030108366.1  semaphorin-6C isoform X18

      Conserved Domains (3) summary
      smart00423
      Location:88 → 109
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:213 → 453
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:1 → 87
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    32. XM_030252493.1 → XP_030108353.1  semaphorin-6C isoform X10

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:606 → 848
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    33. XM_030252496.1 → XP_030108356.1  semaphorin-6C isoform X11

      Conserved Domains (3) summary
      PHA03247
      Location:578 → 821
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    34. XM_036162981.1 → XP_036018874.1  semaphorin-6C isoform X11

      Conserved Domains (3) summary
      PHA03247
      Location:578 → 821
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    35. XM_036162980.1 → XP_036018873.1  semaphorin-6C isoform X10

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:606 → 848
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    36. XM_030252499.1 → XP_030108359.1  semaphorin-6C isoform X11

      Conserved Domains (3) summary
      PHA03247
      Location:578 → 821
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:411 → 432
      PSI; Plexin repeat
      cl15693
      Location:1 → 410
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    37. XM_030252502.2 → XP_030108362.1  semaphorin-6C isoform X15

      Conserved Domains (3) summary
      PHA03247
      Location:539 → 782
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:372 → 393
      PSI; Plexin repeat
      cl15693
      Location:1 → 371
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    38. XM_036162986.1 → XP_036018879.1  semaphorin-6C isoform X15

      Conserved Domains (3) summary
      PHA03247
      Location:539 → 782
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:372 → 393
      PSI; Plexin repeat
      cl15693
      Location:1 → 371
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    39. XM_036162985.1 → XP_036018878.1  semaphorin-6C isoform X14

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:544 → 787
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:377 → 398
      PSI; Plexin repeat
      cl15693
      Location:1 → 376
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    40. XM_006501206.3 → XP_006501269.1  semaphorin-6C isoform X4

      UniProtKB/TrEMBL
      Q91Y36
      Conserved Domains (3) summary
      smart00423
      Location:479 → 500
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:674 → 916
      PHA03247; large tegument protein UL36; Provisional
      cl15693
      Location:39 → 478
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    41. XM_036162979.1 → XP_036018872.1  semaphorin-6C isoform X9

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:611 → 853
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:416 → 437
      PSI; Plexin repeat
      cl15693
      Location:81 → 415
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    42. XM_036162984.1 → XP_036018877.1  semaphorin-6C isoform X13

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:547 → 789
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:352 → 373
      PSI; Plexin repeat
      cl15693
      Location:17 → 351
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    43. XM_036162987.1 → XP_036018880.1  semaphorin-6C isoform X16

      UniProtKB/TrEMBL
      Q6ZPG8
      Conserved Domains (3) summary
      PHA03247
      Location:573 → 815
      PHA03247; large tegument protein UL36; Provisional
      pfam01437
      Location:378 → 399
      PSI; Plexin repeat
      cl15693
      Location:43 → 377
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WTM3.1 GenPept UniProtKB/Swiss-Prot:Q9WTM3

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