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    Rdm1 RAD52 motif 1 [ Mus musculus (house mouse) ]

    Gene ID: 66599, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rdm1provided by MGI
    Official Full Name
    RAD52 motif 1provided by MGI
    Primary source
    MGI:MGI:1913849
    See related
    Ensembl:ENSMUSG00000010362 AllianceGenome:MGI:1913849
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rad52b; 2410008M22Rik
    Summary
    Predicted to enable DNA binding activity and RNA binding activity. Predicted to be located in cytosol. Predicted to be active in nucleolus. Is expressed in brain; central nervous system ganglion; sensory organ; and testis. Orthologous to human RDM1 (RAD52 motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 7.7), thymus adult (RPKM 7.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rdm1 in Genome Data Viewer
    Location:
    11 D; 11 65.48 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101517992..101526926)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101627242..101636089)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30771 Neighboring gene predicted gene, 26316 Neighboring gene STARR-seq mESC enhancer starr_30772 Neighboring gene uncharacterized LOC666331 Neighboring gene STARR-seq mESC enhancer starr_30774 Neighboring gene STARR-seq mESC enhancer starr_30775 Neighboring gene STARR-positive B cell enhancer ABC_E4003 Neighboring gene predicted gene, 23849 Neighboring gene STARR-seq mESC enhancer starr_30777 Neighboring gene predicted gene, 24950 Neighboring gene STARR-positive B cell enhancer ABC_E3024 Neighboring gene predicted gene, 23971

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates. Hamimes S, et al. J Biol Chem, 2005 Mar 11. PMID 15611051
    2. siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors. Böhringer M, et al. Oncogene, 2013 Nov 28. PMID 23435420, Free PMC Article
    3. Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Cheverud JM, et al. Heredity (Edinb), 2014 May. PMID 24569637, Free PMC Article
    4. Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. Liu X, et al. BMC Immunol, 2016 Aug 2. PMID 27480124, Free PMC Article
    5. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RAD52 motif-containing protein 1
    Names
    RAD52 homolog B
    RAD52B homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025654.3 → NP_079930.1  RAD52 motif-containing protein 1

      See identical proteins and their annotated locations for NP_079930.1

      Status: VALIDATED

      Source sequence(s)
      AL590994
      Consensus CDS
      CCDS25477.1
      UniProtKB/Swiss-Prot
      Q9CQK3
      Related
      ENSMUSP00000010506.4, ENSMUST00000010506.10
      Conserved Domains (1) summary
      cd12364
      Location:15 → 95
      RRM_RDM1; RNA recognition motif of RAD52 motif-containing protein 1 (RDM1) and similar proteins

    RNA

    1. NR_184640.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL590994

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      101517992..101526926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533945.4 → XP_006534008.1  RAD52 motif-containing protein 1 isoform X1

      Conserved Domains (1) summary
      cd12364
      Location:14 → 76
      RRM_RDM1; RNA recognition motif of RAD52 motif-containing protein 1 (RDM1) and similar proteins

    2. XM_011249178.4 → XP_011247480.1  RAD52 motif-containing protein 1 isoform X2

      Conserved Domains (1) summary
      cd12364
      Location:15 → 95
      RRM_RDM1; RNA recognition motif of RAD52 motif-containing protein 1 (RDM1) and similar proteins

    RNA

    1. XR_003949490.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQK3.1 GenPept UniProtKB/Swiss-Prot:Q9CQK3

    Gene LinkOut

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