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    Lrrc14b leucine rich repeat containing 14B [ Mus musculus (house mouse) ]

    Gene ID: 432779, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Lrrc14bprovided by MGI
    Official Full Name
    leucine rich repeat containing 14Bprovided by MGI
    Primary source
    MGI:MGI:2145269
    See related
    Ensembl:ENSMUSG00000021579 AllianceGenome:MGI:2145269
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be active in cytoplasm. Orthologous to human LRRC14B (leucine rich repeat containing 14B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in heart adult (RPKM 45.6), mammary gland adult (RPKM 10.2) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc14b in Genome Data Viewer
    Location:
    13 C1; 13 40.22 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74507701..74512119, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (74359582..74364000, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene programmed cell death 6 Neighboring gene succinate dehydrogenase complex, subunit A, flavoprotein (Fp) Neighboring gene STARR-positive B cell enhancer ABC_E10800 Neighboring gene coiled-coil domain containing 127 Neighboring gene zinc finger protein 72 Neighboring gene STARR-seq mESC enhancer starr_35006 Neighboring gene BCL2-like 13 (apoptosis facilitator) pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7251 Neighboring gene STARR-seq mESC enhancer starr_35008 Neighboring gene ferritin light polypeptide 1, pseudogene 1 Neighboring gene microRNA 692-3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 14B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033042.3 → NP_001028214.1  leucine-rich repeat-containing protein 14B

      See identical proteins and their annotated locations for NP_001028214.1

      Status: PROVISIONAL

      Source sequence(s)
      CT009486
      Consensus CDS
      CCDS26645.1
      UniProtKB/Swiss-Prot
      Q3UJB3, Q6P1Y3
      Related
      ENSMUSP00000022064.5, ENSMUST00000022064.5
      Conserved Domains (3) summary
      cd00116
      Location:260 → 397
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:302 → 328
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:302 → 368
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      74507701..74512119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UJB3.1 GenPept UniProtKB/Swiss-Prot:Q3UJB3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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